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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Questioning an axiom: Better prognosis for schizophrenia in the developing world?
Schizophrenia Bulletin, Volume 34, No. 2, Year 2008
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Description
Introduction: That schizophrenia has a better course and outcome in developing countries has become an axiom in international psychiatry. This is based primarily on a series of cross-national studies by the World Health Organization (WHO). However, increasing evidence from other research indicates a far more complex picture. Methods: Literature review and tabulation of data from 23 longitudinal studies of schizophrenia outcomes in 11 low- and middle-income countries. Results: We reviewed the evidence about the following domains: clinical outcomes and patterns of course, disability and social outcomes (marital and occupational status, in particular), and untreated samples and duration of untreated psychosis. Outcomes varied across the studies and the evidence suggests a need to reexamine the conclusions of the WHO studies. Additionally, assessments of outcomes should take excess mortality and suicide into account. Conclusions: It is time to reexamine presumed wisdom about schizophrenia outcomes in low- and middle-income countries. © 2007 The Authors.
Authors & Co-Authors
Cohen, Alex M.
Unknown Affiliation
Patel, Vikram Harshad
Unknown Affiliation
Thara, Rangaswamy
Unknown Affiliation
Gureje, Oye
Unknown Affiliation
Statistics
Citations: 242
Authors: 4
Affiliations: 5
Identifiers
Doi:
10.1093/schbul/sbm105
ISSN:
05867614
e-ISSN:
17451701
Research Areas
Disability
Mental Health
Study Design
Cohort Study
Study Approach
Systematic review