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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Pulmonary tuberculosis and HIV seropositivity at the Principal Hospital of Dakar, Senegal
La Revue de medecine interne, Volume 14, No. 1, Year 1993
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Description
In a prospective survey conducted in 1990 in the Principal Hospital of Dakar, pulmonary tuberculosis was 2.3 times more frequent in HIV seropositive patients (12.5 %) than in HIV seronegative patients. We studied 22 cases of pulmonary tuberculosis in HIV+ patients and compared them with a control group of HIV- patients admitted for pulmonary tuberculosis. Tuberculosis occurred in 6 out of 22 asymptomatic HIV + patients, in 15 out of 22 patients with clinical AIDS and in 1 patient with ARC syndrome. Clinical signs were the same as in controls, except for patients with advanced AIDS who developed cardinal signs. TB intra-dermal reactions were more often negative in HIV + patients, notably those with HDV1, expressing immunodepression. Radiological images were typical in 81 % of patients and in 86 % of controls. However, concomitant infections were common in both groups, with atypical radiology and hyperleucocytosis. At light microscopy, there was no difference in the frequency of acid and alcohol fast bacilli between the two groups. The mortality rate was increased in HIV + patients, but this was not due to tuberculosis. Relapses were frequent in both groups, due to poor compliance with treatment. © 1993.
Authors & Co-Authors
Brucker-Davis, Françoise
Senegal, Dakar
Institut Pasteur de Dakar
Le Guenno, Bernard M.
Senegal, Dakar
Institut Pasteur de Dakar
Bah, A.
Senegal, Dakar
Institut Pasteur de Dakar
Griffet, Philippe A.
Senegal
Hôpital Principal
Launois, Pascal
Senegal, Dakar
Institut Pasteur de Dakar
Statistics
Citations: 5
Authors: 5
Affiliations: 2
Identifiers
Doi:
10.1016/S0248-8663(05)82516-0
ISSN:
02488663
e-ISSN:
17683122
Research Areas
Health System And Policy
Infectious Diseases
Substance Abuse
Study Design
Randomised Control Trial
Cross Sectional Study
Cohort Study
Study Approach
Quantitative
Study Locations
Senegal