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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: Updated recommendations from the World Health Organization Pneumococcal Carriage Working Group
Vaccine, Volume 32, No. 1, Year 2013
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Description
In 2003 the World Health Organization (WHO) convened a working group and published a set of standard methods for studies measuring nasopharyngeal carriage of Streptococcus pneumoniae (the pneumococcus). The working group recently reconvened under the auspices of the WHO and updated the consensus standard methods. These methods describe the collection, transport and storage of nasopharyngeal samples, as well as provide recommendations for the identification and serotyping of pneumococci using culture and non-culture based approaches. We outline the consensus position of the working group, the evidence supporting this position, areas worthy of future research, and the epidemiological role of carriage studies. Adherence to these methods will reduce variability in the conduct of pneumococcal carriage studies undertaken in the context of pneumococcal vaccine trials, implementation studies, and epidemiology studies more generally so variability in methodology does not confound the interpretation of study findings. © 2013 Elsevier Ltd.
Authors & Co-Authors
Satzke, Catherine
Unknown Affiliation
Turner, Paul D.
Unknown Affiliation
Virolainen-Julkunen, Anni
Unknown Affiliation
Adrian, Peter V.
Unknown Affiliation
Antonio, Martin
Unknown Affiliation
Hare, K.
Unknown Affiliation
Henao-Restrepo, Ana Maria
Unknown Affiliation
Leach, Amanda Jane
Unknown Affiliation
Klugman, K. P.
Unknown Affiliation
Porter, Barbara D.
Unknown Affiliation
Sa-Leao, R.
Unknown Affiliation
Scott, John Anthony Gerard
Unknown Affiliation
Nohynek, Hanna M.
Unknown Affiliation
O'Brien, Katherine L.
Unknown Affiliation
Statistics
Citations: 376
Authors: 14
Affiliations: 19
Identifiers
Doi:
10.1016/j.vaccine.2013.08.062
ISSN:
0264410X
e-ISSN:
18732518