Picogram level determination of fluphenazine in human plasma by automated gas chromatography/mass selective detection

An automated capillary column gas chromatography electron‐impact mass selective detection method has been developed for the determination of a major tranquilizing agent, fluphenazine. Using a new purification method and incorporating a deuterated internal reference, a limit of quantitation of 50 pg per ml of plasma was obtained. Copyright © 1987 John Wiley & Sons Ltd.