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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Dephytinisation with Intrinsic Wheat Phytase and Iron Fortification Significantly Increase Iron Absorption from Fonio (Digitaria exilis) Meals in West African Women
PLoS ONE, Volume 8, No. 10, Article e70613, Year 2013
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Description
Low iron and high phytic acid content make fonio based meals a poor source of bioavailable iron. Phytic acid degradation in fonio porridge using whole grain cereals as phytase source and effect on iron bioavailability when added to iron fortified fonio meals were investigated. Grains, nuts and seeds collected in Mali markets were screened for phytic acid and phytase activity. We performed an iron absorption study in Beninese women (n = 16), using non-dephytinised fonio porridge (FFP) and dephytinised fonio porridge (FWFP; 75% fonio-25% wheat), each fortified with 57Fe or 58Fe labeled FeSO4. Iron absorption was quantified by measuring the erythrocyte incorporation of stable iron isotopes. Phytic acid varied from 0.39 (bambara nut) to 4.26 g/100 g DM (pumpkin seed), with oilseeds values higher than grains and nuts. Phytase activity ranged from 0.17±1.61 (fonio) to 2.9±1.3 phytase unit (PU) per g (whole wheat). Phytic acid was almost completely degraded in FWFP after 60 min of incubation (pH≈5.0, 50°C). Phytate:iron molar ratios decreased from 23.7:1 in FFP to 2.7:1 in FWFP. Iron fortification further reduced phytate:iron molar ratio to 1.9:1 in FFP and 0.3:1 in FWFP, respectively. Geometric mean (95% CI) iron absorption significantly increased from 2.6% (0.8-7.8) in FFP to 8.3% (3.8-17.9) in FWFP (P<0.0001). Dephytinisation of fonio porridge with intrinsic wheat phytase increased fractional iron absorption 3.2 times, suggesting it could be a possible strategy to decrease PA in cereal-based porridges. © 2013 Koréissi-Dembélé et al.
Authors & Co-Authors
Koréissi-Dembélé, Yara
Unknown Affiliation
Fanou-Fogny, Nadia
Unknown Affiliation
Moretti, Diego
Unknown Affiliation
Schuth, S.
Unknown Affiliation
Dossa, Romain A.M.
Unknown Affiliation
Egli, Ines M.
Unknown Affiliation
Zimmermann, Michaël Bruce
Unknown Affiliation
Brouwer, Inge D.
Unknown Affiliation
Statistics
Citations: 31
Authors: 8
Affiliations: 6
Identifiers
Doi:
10.1371/journal.pone.0070613
e-ISSN:
19326203
Study Locations
Mali
Participants Gender
Female