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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Seroepidemiological Studies of HTLV-III Antibody Prevalence Among Selected Groups of Heterosexual Africans
JAMA: The Journal of the American Medical Association, Volume 254, No. 18, Year 1985
Notification
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Description
T-lymphocyte subsets and human T-cell lymphotropic virus type III antibody prevalence were studied in African patients with the acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC), and in female prostitutes. African blood donors and healthy Zairian and Rwandese persons matched for age, sex, and annual income served as controls. Seropositivity was noted in 46 (87%) of 53 patients with AIDS, 29 (88%) of 33 patients with ARC, 67 (80%) of 84 prostitutes, and five (12.5%) of 40 and eight (15.5%) of 51 healthy controls and blood donors,respectively. Patients with AIDS and ARC had a significantly lower OKT4/OKT8 ratio than healthy African controls. These studies suggest that human T-cell lymphotropic virus type III infection has already spread extensively into the general African population and that female prostitutes could be an important human reservoir of AIDS virus in the heterosexual population. © 1985, American Medical Association. All rights reserved.
Authors & Co-Authors
Clumeck, Nathan N.
United States, Brussels
Centre Hospitalier Universitaire St. Pierre
Robert-Guroff, Marjorie G.
United States, Rockville
National Cancer Institute Nci
van de Perre, Philippe
United States, Brussels
Centre Hospitalier Universitaire St. Pierre
Jennings, Andrea M.
United States, Rockville
National Cancer Institute Nci
Sibomana, Jean
Rwanda, Kigali
Blood Transfusion Project
Demol, Patrick
United States, Brussels
Centre Hospitalier Universitaire St. Pierre
Cran, Sophie
United States, Brussels
Centre Hospitalier Universitaire St. Pierre
Gallo, Robert C.
United States, Rockville
National Cancer Institute Nci
Statistics
Citations: 70
Authors: 8
Affiliations: 3
Identifiers
Doi:
10.1001/jama.1985.03360180103034
ISSN:
00987484
e-ISSN:
15383598
Research Areas
Infectious Diseases
Study Design
Cross Sectional Study
Participants Gender
Female