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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Survey on acute and chronic complications in children and adolescents with type 1 diabetes at Muhimbili National Hospital in Dar es Salaam, Tanzania
Diabetes Care, Volume 30, No. 9, Year 2007
Notification
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Description
OBJECTIVE - The purpose of this study was to assess glycemic control and complications of type 1 diabetes in children and adolescents in Tanzania. RESEARCH DESIGN AND METHODS - This demographic and clinical survey included 99 children aged between 5 and 18 years attending Muhimbili National Hospital Clinic for Diabetes. A structured questionnaire was used for evaluating socioeconomic data and for estimation of the prevalence of acute complications occurring over the last 6 months. The prevalences of retinopathy and diabetic nephropathy were determined by fundus ophthalmoscopy and by microalbuminuria, respectively. RESULTS - All of these children were treated with a conventional insulin regimen. The mean ± SD duration of diabetes was 4.76 ± 3.58 years. Only 1 child (1%) had good glycemic control (A1C < 7.5%), 60 children (60.6%) had moderate glycemic control (A1C 7.5-10%), 14 children (14.1%) had poor glycemic control (A1C > 10-12.5%), and 24 children (24.2%) had very poor glycemic control (A1C > 12.5%). At onset of diabetes, 75% of children presented with diabetic ketoacidosis (DKA); 89 children (89.80%) had at least one episode of DKA, and 55 children (55.67%) had symptomatic hypoglycemic episodes. Microalbuminuria was present in 29 (29.3%) and retinopathy in 22 (22.68%) children. CONCLUSIONS - Although there are some methodological limitations, this survey highlights the difficulties of achieving good metabolic control and the high prevalence of acute and chronic complications in Tanzanian children with type 1 diabetes. These results clearly show that major efforts are needed to improve quality of care in children with type 1 diabetes in Tanzania. © 2007 by the American Diabetes Association.
Authors & Co-Authors
Majaliwa, Edna Siima
Italy, Chieti
University of G. D'annunzio Chieti and Pescara
Tanzania, Dar es Salaam
Muhimbili University of Health and Allied Sciences
Munubhi, Emmanuel K.D.
Tanzania, Dar es Salaam
Muhimbili University of Health and Allied Sciences
Ramaiya, Kaushik Laxmidas
Tanzania, Dar es Salaam
Shree Hindu Mandal Hospital
Mpembeni, Rose N.M.
Tanzania, Dar es Salaam
Muhimbili University of Health and Allied Sciences
Sanyiwa, Anna J.
Tanzania, Dar es Salaam
Muhimbili National Hospital
Mohn, Angelika
Italy, Chieti
University of G. D'annunzio Chieti and Pescara
Chiarelli, Francesco G.
Italy, Chieti
University of G. D'annunzio Chieti and Pescara
Statistics
Citations: 7
Authors: 7
Affiliations: 4
Identifiers
Doi:
10.2337/dc07-0594
ISSN:
01495992
e-ISSN:
01495992
Research Areas
Health System And Policy
Maternal And Child Health
Noncommunicable Diseases
Study Design
Cross Sectional Study
Study Approach
Quantitative
Study Locations
Tanzania