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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Does the association between birth weight and blood pressure increase with age? A longitudinal study in young adults
Journal of Hypertension, Volume 34, No. 6, Year 2016
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Description
Objectives: To assess whether the association between birth weight and blood pressure (BP) increases with age using three different statistical methods. Methods: A representative sample of 1232 study participants born between 1974-1978 in Limache, Chile were assessed in 2000-2002, of whom 796 were reassessed in 2010-2012. An 'amplification effect' was assessed by the change in the β coefficient in the two periods, the association between birth weight and the difference of BP overtime, and the interaction between birth weight and BP in the two periods. Results: Birth weight was negatively associated with SBP in 2000-2002 (β = -2.46, 95% confidence interval (CI) -3.77 to -1.16) and in 2010-2012 (β = -3.64, 95% CI -5.20 to -2.08), and with DBP in 2000-2002 (β = -1.26, 95% CI -2.23 to -0.29), and 2010-2012 (β = -1.64, 95% CI -2.84 to -0.45) after adjustment for sex, physical activity, and BMI. There was no association between birth weight and the difference in BP between the two periods or the interaction between birth weight, BP, and time interval. Conclusion: Birth weight is a factor associated with BP in adults. This association increased with age, but amplification was shown only with one of the three methods. © Copyright 2016 Wolters Kluwer Health, Inc. All rights reserved.
Authors & Co-Authors
Bustos, Patricia
Chile, Santiago
Facultad de Medicina de la Universidad de Chile
Amigo, Hugo
Chile, Santiago
Facultad de Medicina de la Universidad de Chile
Bangdiwala, Shrikant I.
United States, Chapel Hill
The University of North Carolina at Chapel Hill
Statistics
Citations: 4
Authors: 3
Affiliations: 4
Identifiers
Doi:
10.1097/HJH.0000000000000912
ISSN:
02636352
Research Areas
Noncommunicable Diseases
Study Design
Cohort Study
Study Approach
Quantitative