Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Patient retention and attrition on antiretroviral treatment at district level in rural Malawi
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 103, No. 6, Year 2009
Notification
URL copied to clipboard!
Description
We report on rates of patient retention and attrition in the context of scaling-up antiretroviral treatment (ART) within a district hospital and its primary health centres in rural Malawi. 'Retention' was defined as being alive and on ART or transferred out, whereas 'attrition' was defined as died, lost to follow-up or stopped treatment. A total of 4074 patients were followed-up for 1803 person-years: 2904 were at the hospital and 1170 at health centres. Approximately 85% of patients were retained in care, both at hospital and health centres, with a retention rate per 100 person-years of 185 and 211, respectively [adjusted hazard ratio (HR) 1.18, 95% CI 1.10-1.28, P = 0.001). Attrition rates per 100 person-years were similar: 33 and 36, respectively (adjusted HR 1.17, 95% CI 0.97-1.4, P = 0.1). At health centres the incidence of loss to follow-up was significantly lower than at the hospital (adjusted HR 0.24, P < 0.001, risk reduction 77%), but the rate of reported deaths was higher at health centres (adjusted HR 2.2, 95% CI 1.76-2.72, P < 0.001). As Malawi continues to extend the coverage (and equity) of ART, including in rural areas, attention is needed to reduce losses to follow-up at hospital level and reduce mortality at primary care level. © 2009 Royal Society of Tropical Medicine and Hygiene.
Authors & Co-Authors
Massaquoi, Moses B.F.
Unknown Affiliation
Zachariah, Rony R.Z.
Unknown Affiliation
Manzi, Marcel
Unknown Affiliation
Pasulani, Olesi
Unknown Affiliation
Misindi, D.
Unknown Affiliation
Matanje-Mwagomba, Beatrice L.
Unknown Affiliation
Bauernfeind, Ariane
Unknown Affiliation
Harries, Anthony David
Unknown Affiliation
Statistics
Citations: 100
Authors: 8
Affiliations: 6
Identifiers
Doi:
10.1016/j.trstmh.2009.02.012
ISSN:
00359203
Research Areas
Environmental
Health System And Policy
Study Design
Cohort Study
Study Locations
Malawi