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Cabotegravir is not associated with weight gain in human immunodeficiency virus-uninfected individuals in HPTN 077

Clinical Infectious Diseases, Volume 70, No. 2, Year 2020

Studies in human immunodeficiency virus (HIV)-infected individuals suggest excess weight gain with integrase inhibitor- based antiretroviral therapy. The HIV Prevention Trials Network Study 077 evaluated changes in weight and fasting metabolic parameters in HIV-uninfected individuals randomized to cabotegravir or a placebo. No differences between arms were found for change in weight or fasting metabolic parameters overall or for subgroups.

https://efashare.b-cdn.net/share/pmc/articles/PMC6938971/bin/ciz439_suppl_supplementary_material.docx

Landovitz, Raphael J.
1. United States, Los Angeles David Geffen School of Medicine at Ucla
Zangeneh, Sahar Z.
1. United States, Seattle Fred Hutchinson Cancer Research Center
Chau, Gordon
1. United States, Seattle Fred Hutchinson Cancer Research Center
Grinsztejn, Beatriz Gilda Jegerhorn
1. Brazil, Rio de Janeiro Instituto Nacional de Infectologia Evandro Chagas Ini
Eron, Joseph J.
1. United States, Chapel Hill The University of North Carolina at Chapel Hill
Dawood, Haiima
1. South Africa, Durban University of Kwazulu-natal
Magnus, Manya
1. United States, Washington, D.c. The George Washington University
Liu, Albert Y.
1. United States, San Francisco San Francisco Department of Public Health
Panchia, Ravindre
1. South Africa, Johannesburg Chris Hani Baragwanath Hospital
Hosseinipour, Mina C.
1. United States, Chapel Hill The University of North Carolina at Chapel Hill
Kofron, Ryan M.
1. United States, Los Angeles David Geffen School of Medicine at Ucla
Margolis, David A.
1. United Kingdom, Brentford Viiv Healthcare
Rinehart, Alex R.
1. United Kingdom, Brentford Viiv Healthcare
Adeyeye, Adeola O.
1. United States, Bethesda National Institute of Allergy and Infectious Diseases Niaid
Burns, David N.
1. United States, Bethesda National Institute of Allergy and Infectious Diseases Niaid
McCauley, Marybeth B.
1. United States, Durham Fhi 360
Cohen, Myron S.
1. United States, Chapel Hill The University of North Carolina at Chapel Hill
Currier, Judith Silverstein
1. United States, Los Angeles David Geffen School of Medicine at Ucla

AFRICAN RESEARCH NEXUS

Cabotegravir is not associated with weight gain in human immunodeficiency virus-uninfected individuals in HPTN 077

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AFRICAN RESEARCH NEXUS

Cabotegravir is not associated with weight gain in human immunodeficiency virus-uninfected individuals in HPTN 077

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