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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
chemistry
Development of CMC hydrogels loaded with silver nano-particles for medical applications
Carbohydrate Polymers, Volume 92, No. 1, Year 2013
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Description
Innovative CMC-based hydrogels with great potentials for usage in medical area were principally synthesized as per two strategies.The first involved reaction of epichlorohydrin in alkaline medium containing silver nitrate to yield silver nano-particles (AgNPs)-loaded CMC hydrogel. While CMC acted as stabilizing for AgNPs, trisodium citrate was added to the reaction medium to assist CMC in establishing reduction of Ag+ to AgNPs. The second strategy entailed preparation of CMC hydrogel which assists the in situ preparation of AgNPs under the same conditions. In both strategies, factors affecting the characterization of AgNPs-loaded CMC hydrogels were studied. Analysis and characterization of the so obtained hydrogels were performed through monitoring swelling behavior, FTIR spectroscopy, SEM, EDX, UV-vis spectrophotometer and TEM. Antimicrobial activity of the hydrogels was examined and mechanisms involved in their synthesis were reported. © 2012 Elsevier Ltd. All rights reserved.
Authors & Co-Authors
Hebeish, Ali Ali
Egypt, Giza
National Research Centre
Hashem, Mohamed M.
Egypt, Giza
National Research Centre
Abd El-Hady, M. M.
Egypt, Giza
National Research Centre
Sharaf, Samar S.
Egypt, Giza
National Research Centre
Statistics
Citations: 255
Authors: 4
Affiliations: 1
Identifiers
Doi:
10.1016/j.carbpol.2012.08.094
ISSN:
01448617