Alkaloids from rhamnaceae-XXVI. Nummularine -D, -E and -F, new cyclopeptide alkaloids from Zizyphus nummularia

From the benzene extract of the root bark of Zizyphus nummularia three new peptide alkaloids have been isolated: nummularine-D 1, -E 3 and -F 5. All three contain the 14-membered ring system. Nummularine-D is N-desmethyl-integerrenine. Nummularine-E has N,N-dimethylthreonine and nummularine-F has N,N-dimethylglycine as terminal amino-acid, neither of which has been found in such alkaloids before. © 1975.