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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Self-esteem and neuroendocrine response to challenge: MacArthur studies of successful aging
Journal of Psychosomatic Research, Volume 39, No. 1, Year 1995
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Description
The role of self-esteem in modulating patterns of neuroendocrine response to challenge at older ages was examined in 16 healthy 70-yr-olds. Responses to two challenges were examined: (1) a driving simulation designed to reflect a 'real life' challenge situation; and (2) a pharmacologic, corticotropin-releasing-hormone (CRH) challenge (1 μg/kg). Both challenges evoked significant elevations in cortisol and adrenocorticotropic hormone (ACTH). Levels of self-esteem were significantly and negatively associated with peak elevations in cortisol in response to the driving simulation challenge (r = -0·51, p = 0·04). ACTH responses showed similar trends (r = -0·41, p = 0·12). Self-esteem levels were not correlated with responses to the CRH challenge. These data indicate that psychological characteristics such as self-esteem may play a role in modulating patterns of neuroendocrine response to cognitive/behavioral challenges in everyday life in older individuals. © 1995.
Authors & Co-Authors
Berkman, Lisa F.
United States, New Haven
Yale University
Greenspan, Susan L.
United States, Boston
Beth Israel Deaconess Medical Center
Statistics
Citations: 88
Authors: 2
Affiliations: 3
Identifiers
Doi:
10.1016/0022-3999(94)00076-H
ISSN:
00223999