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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Profile of crescentic glomerulonephritis in natal - a clinicopathological assessment
QJM, Volume 68, No. 2, Year 1988
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Description
Crescentic glomerulonephritis is invariably associated with a fulminant syndrome of rapidly progressive renal failure which generally progresses to end-stage renal failure within weeks or months of onset. A widely differing aetiological background has been reported from Western countries. Work from the African continent is sparse. In a study from the province of Natal in South Africa between 1981 and 1987, 27 cases of crescentic nephritis were identified from a total of 458 patients who underwent renal biopsy at King Edward VIII and Addington hospitals. Poststreptococcal nephritis was the commonest aetiological factor (n=8). There were six black patients in this group. Nine patients were classified as idiopathic and of these five were black. Four patients (one black) had antiglomerular basement membrane disease. Of the 24 patients subjected to variable combinations of immunosuppression, antiplatelet agents, dialysis and plasmapheresis, 11 improved, observed over four months to four years. Oliguria and severe renal failure at presentation signified a poor prognosis. © Oxford University Press.
Authors & Co-Authors
Parag, Kantilal B.
South Africa, Congella
University of Natal, Faculty of Medicine
Naran, Anupam D.
South Africa, Congella
University of Natal, Faculty of Medicine
Seedat, Yackoob Kassim
South Africa, Congella
University of Natal, Faculty of Medicine
Nathoo, Bharat C.
South Africa, Congella
University of Natal, Faculty of Medicine
Naiker, Indiran P.
South Africa, Congella
University of Natal, Faculty of Medicine
Naicker, Saraladevi
South Africa, Congella
University of Natal, Faculty of Medicine
Statistics
Citations: 6
Authors: 6
Affiliations: 1
Identifiers
Doi:
10.1093/oxfordjournals.qjmed.a068230
ISSN:
14602725
e-ISSN:
14602393
Research Areas
Noncommunicable Diseases
Study Locations
South Africa