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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
What is the impact on sexual function of laparoscopic treatment and subsequent combined oral contraceptive therapy in women with deep infiltrating endometriosis?
Journal of Sexual Medicine, Volume 9, No. 3, Year 2012
Notification
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Description
Introduction. Deep infiltrating endometriosis (DIE) is a form of endometriosis in which the lesion penetrates for more than 5mm under the peritoneal surface. It is a chronic disease which can impair women's sexual function. There is a growing body of evidence supporting combined surgical/medical treatment in the management of DIE. Aims. The aims of this article are to evaluate the impact of the laparoscopic full excision of endometriosis and postoperative combined oral contraceptives (COC) administration on sexual function in patients with DIE and to compare sexual function outcomes of women submitted to intestinal resection and nodule excision. Methods. It is a prospective cohort study in a tertiary care university hospital on 106 sexually active women, with histologically confirmed DIE, managed by laparoscopy and subsequent COC therapy for 6 months. Patients filled preoperatively and 6-month postoperatively a quality of sexual life questionnaire, the Sexual Health Outcomes in Women Questionnaire (SHOW-Q) and they ranked their symptom intensity using a 10-point visual analogue scale (VAS). Main Outcome Measures. Sexual function was measured through the SHOW-Q scores and pain symptoms through VAS scores. Intraoperative details, type of intervention and perioperative complications were noted. Results. Six months after surgery and postoperative COC treatment, a significant improvement was observed in the SHOW-Q domains of pelvic problem interference, sexual satisfaction and desire (P<0.05). Laparoscopic management of DIE did not change significantly the orgasm area of the sexual functioning (P=0.7). No significant difference was found in SHOW-Q scores between patients submitted to intestinal resection and patients submitted to intestinal nodule excision (P>0.05). Conclusions. Sexual desire, satisfaction with sex and pelvic problem interference with intercourse are significantly improved after 6 months from laparoscopic excision of DIE combined with postoperative COC therapy. No difference in sexual outcomes was detected between patients submitted to intestinal resection and nodule excision. © 2012 International Society for Sexual Medicine.
Authors & Co-Authors
Mabrouk, Mohamed H.
Italy, Bologna
Irccs Azienda Ospedaliero-universitaria Di Bologna
Egypt, Alexandria
Faculty of Medicine
Montanari, Giulia
Italy, Bologna
Irccs Azienda Ospedaliero-universitaria Di Bologna
Di Donato, Nadine D.
Italy, Bologna
Irccs Azienda Ospedaliero-universitaria Di Bologna
del Forno, Simona
Italy, Bologna
Irccs Azienda Ospedaliero-universitaria Di Bologna
Frascá, Clarissa
Italy, Bologna
Irccs Azienda Ospedaliero-universitaria Di Bologna
Geraci, Elisa
Italy, Bologna
Irccs Azienda Ospedaliero-universitaria Di Bologna
Ferrini, Giulia
Italy, Bologna
Irccs Azienda Ospedaliero-universitaria Di Bologna
Vicenzi, Claudia
Italy, Bologna
Irccs Azienda Ospedaliero-universitaria Di Bologna
Raimondo, D.
Italy, Bologna
Irccs Azienda Ospedaliero-universitaria Di Bologna
Villa, Gioia
Italy, Bologna
Irccs Azienda Ospedaliero-universitaria Di Bologna
Zukerman, Ziv
Italy, Bologna
Irccs Azienda Ospedaliero-universitaria Di Bologna
Alvisi, Stefania
Italy, Bologna
Irccs Azienda Ospedaliero-universitaria Di Bologna
Seracchioli, Renato
Italy, Bologna
Irccs Azienda Ospedaliero-universitaria Di Bologna
Statistics
Citations: 51
Authors: 13
Affiliations: 2
Identifiers
Doi:
10.1111/j.1743-6109.2011.02593.x
ISSN:
17436095
e-ISSN:
17436109
Research Areas
Health System And Policy
Sexual And Reproductive Health
Study Design
Randomised Control Trial
Cohort Study
Study Approach
Quantitative
Participants Gender
Female