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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
The spectrum of ABO hemolytic disease of the newborn infant
The Journal of Pediatrics, Volume 95, No. 3, Year 1979
Notification
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Description
A series of 1,704 infants of blood group O mothers have been studied to determine the relation between the degree of red cell sensitization and the cord hemoglobin and bilirubin concentrations. The infants with blood group A or B had significantly higher cord bilirubin and lower cord hemoglobin concentrations than the group O babies. Those infants whose red cells had the greatest evidence of sensitization had the highest bilirubin and lowest hemoglobin levels. The infants in whom no antibody was demonstrable on the red cells or in the red cell eluate also had significantly higher cord bilirubin and lower cord hemoglobin levels than the ABO compatible group; it is suggested that these infants had sufficient erythrocyte sensitization to produce mild hemolysis. ABO incompatibility represents a spectrum of hemolytic disease extending from those in which there is little laboratory evidence of erythrocyte sensitization, but evidence of hemolysis, to severe hemolytic disease in which erythrocyte sensitization is usually easily demonstrable. © 1979 The C. V. Mosby Company.
Authors & Co-Authors
Blajchman, Morris A.
Canada, Hamilton
Mcmaster University
Canada, Ottawa
Canadian Red Cross Society
Chintu, Chifumbe Z.
Canada, Hamilton
Mcmaster University
Canada, Ottawa
Canadian Red Cross Society
Zipursky, Alvin
Canada, Hamilton
Mcmaster University
Canada, Ottawa
Canadian Red Cross Society
Statistics
Citations: 42
Authors: 3
Affiliations: 2
Identifiers
Doi:
10.1016/S0022-3476(79)80533-8
ISSN:
00223476
Research Areas
Maternal And Child Health