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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Validation of a core outcome measure for palliative care in Africa: The APCA African Palliative Outcome Scale
Health and Quality of Life Outcomes, Volume 8, Article 10, Year 2010
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Description
Background: Despite the burden of progressive incurable disease in Africa, there is almost no evidence on patient care or outcomes. A primary reason has been the lack of appropriate locally-validated outcome tools. This study aimed to validate a multidimensional scale (the APCA African Palliative Outcome Scale) in a multi-centred international study.Methods: Validation was conducted across 5 African services and in 3 phases: Phase 1. Face validity: content analysis of qualitative interviews and cognitive interviewing of POS; Phase 2. Construct validity: correlation of POS with Missoula-Vitas Quality of Life Index (Spearman's rank tests); Phase 3. Internal consistency (Cronbach's alpha calculated twice using 2 datasets), test-retest reliability (intraclass correlation coefficients calculated for 2 time points) and time to complete (calculated twice using 2 datasets).Results: The validation involved 682 patients and 437 family carers, interviewed in 8 different languages. Phase 1. Qualitative interviews (N = 90 patients; N = 38 carers) showed POS items mapped well onto identified needs; cognitive interviews (N = 73 patients; N = 29 carers) demonstrated good interpretation; Phase 2. POS-MVQoLI Spearman's rank correlations were low-moderate as expected (N = 285); Phase 3. (N = 307, 2nd assessment mean 21.2 hours after first, SD 7.2) Cronbach's Alpha was 0.6 on both datasets, indicating expected moderate internal consistency; test-retest found high intra-class correlation coefficients for all items (0.78-0.89); median time to complete 7 mins, reducing to 5 mins at second visit.Conclusions: The APCA African POS has sound psychometric properties, is well comprehended and brief to use. Application of this tool offers the opportunity to at last address the omissions of palliative care research in Africa. © 2010 Harding et al; licensee BioMed Central Ltd.
Available Materials
https://efashare.b-cdn.net/share/pmc/articles/PMC2825183/bin/1477-7525-8-10-S1.DOC
Authors & Co-Authors
Harding, Richard
United Kingdom, London
King's College London
Ellen Selman, Lucy Ellen
United Kingdom, London
King's College London
Agupio, Godfrey
Uganda, Kampala
Hospice Africa Uganda
Dinat, Natalya
South Africa, Johannesburg
Witwatersrand Palliative Care
Gwyther, Liz
South Africa, Cape Town
Hospice Palliative Care Association of South Africa
Mashao, Thandi
South Africa, Cape Town
University of Cape Town
Mmoledi, Keletso
South Africa, Johannesburg
Witwatersrand Palliative Care
Moll, Tony
South Africa, Kwazulu-natal
Church of Scotland Hospital
Sebuyira, Lydia Mpanga
Uganda, Kampala
Makerere University
Panjatovic, Barbara
South Africa, Pietermaritzburg
Msunduzi Hospice
Higginson, Irene J.
United Kingdom, London
King's College London
Statistics
Citations: 162
Authors: 11
Affiliations: 9
Identifiers
Doi:
10.1186/1477-7525-8-10
e-ISSN:
14777525
Research Areas
Disability
Health System And Policy
Study Approach
Qualitative