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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Three new diterpenes and the biological activity of different extracts of Jasonia montana
Natural Product Research, Volume 19, No. 3, Year 2005
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Description
Three new diterpenes, namely jasonin-a (1), jasonin-b (2), and jasonin-c (3) were isolated from the aerial parts of Jasonia montana (Asteraceae). Their structures were elucidated on the basis of spectral data as [(1E)-2-((2S)-1,2,5-trimethylbicyclo[3.2.1]octan-8-yl)vinyl] benzene-3-carboxylic acid (1), [3-((2S, 5S)-1,2, 5-trimethyleycloheptanyl)propyl]benzene-3-carboxylic acid (2), and [(1E)-3-((7R)-1,7-dimethy-4-methylenecycloheptanyl)prop-1-enyl] benzene-3-carboxylic acid (3). In addition, the previously reported 5,7,3′-trihydroxy3,6,4′-trimethoxy flavone designated as centaureidin (4), was also isolated and characterized from this source. The different extracts of the plant were also screened for hypoglycemic, antidiabetic, and antimicrobial activities, wherein the petroleum ether and ethanolic extracts exhibited hypoglycemic and antidiabetic activity, and the petroleum ether and chloroform extracts showed antimicrobial activity. © 2005 Taylor & Francis Ltd.
Authors & Co-Authors
Al-Howiriny, Tawfeq Abdullah
Saudi Arabia, Riyadh
College of Pharmacy
Al-Rehaily, Adnan Jathlan
Saudi Arabia, Riyadh
College of Pharmacy
Pols, Joanna R.
United States, Philadelphia
Philadelphia College of Pharmacy
Porter, John R.
United States, Philadelphia
Philadelphia College of Pharmacy
Mossa, Jaber S.
Saudi Arabia, Riyadh
College of Pharmacy
Ahmed, Bahar
Saudi Arabia, Riyadh
College of Pharmacy
Statistics
Citations: 31
Authors: 6
Affiliations: 2
Identifiers
Doi:
10.1080/14786410410001712715
ISSN:
14786419