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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Influence of parity on bone mineral density and peripheral fracture risk in Moroccan postmenopausal women
Maturitas, Volume 57, No. 4, Year 2007
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Description
The aims of the study were to determine: (1) the relationship between parity and bone mineral density (BMD); (2) the relationship between parity and osteoporotic peripheral fractures. Material and methods: The group studied included 730 postmenopausal women. Patients were separated into four groups according to the number of fullterm pregnancies, group 1: nulliparae, group 2: one to three pregnancies, group 3: four to five pregnancies, and group 4: six and more pregnancies. Additionally, patients were separated into three groups according to their ages, as <50 years, 50-59 years and ≥60 years. Results: The median parity was 4 [0-20]. All the patients with parity greater than six had spine and hip BMD values significantly lower than values in the other groups (p < 0.001). After adjustment for age and body mass index (BMI), decreased lumbar and total hip BMD were still associated to increased parity (analysis of covariance (ANCOVA), p = 0.04 and 0.023, respectively). The relation between parity and lumbar BMD was highly significant among women aged <50 years (age-adjusted p = 0.022), while there was no parity-spine BMD association in the other age groups. The relation between parity and hip BMD was seen only in the group 50-59 years (age-adjusted p = 0.042). A positive history for peripheral fractures was present in 170 (23%) patients. There was relationship between parity and peripheral fractures neither in the whole population nor in the sub-groups according to age. Discussion: The present study suggests that the BMD of the spine and hip decreases with an increasing number of pregnancies, and this situation shows variations in different age groups. However, there was no correlation between parity level and peripheral fractures. © 2007.
Authors & Co-Authors
Allali, Fadoua
Morocco, Sale
El Ayachi University Hospital
Morocco, Rabat
Faculté de Médecine et de Pharmacie de Rabat
Maaroufi, Houda
Morocco, Sale
El Ayachi University Hospital
Aichaoui, Siham El
Morocco, Sale
El Ayachi University Hospital
Khazani, Hamza
Morocco, Sale
El Ayachi University Hospital
Saoud, Bouchra
Morocco, Sale
El Ayachi University Hospital
Benyahya, Boubker
Morocco, Sale
El Ayachi University Hospital
Abouqal, Redouane
Morocco, Rabat
Faculté de Médecine et de Pharmacie de Rabat
Hajjaj-Hassouni, Najia
Morocco, Sale
El Ayachi University Hospital
Morocco, Rabat
Faculté de Médecine et de Pharmacie de Rabat
Statistics
Citations: 61
Authors: 8
Affiliations: 2
Identifiers
Doi:
10.1016/j.maturitas.2007.04.006
ISSN:
03785122
Research Areas
Violence And Injury
Study Design
Cross Sectional Study
Participants Gender
Female