Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
High prevalence of subclinical atherosclerosis in psoriatic arthritis patients without clinically evident cardiovascular disease or classic atherosclerosis risk factors
Arthritis Care and Research, Volume 57, No. 6, Year 2007
Notification
URL copied to clipboard!
Description
Objective. To assess the presence of subclinical atherosclerosis in patients with psoriatic arthritis (PsA) without clinically evident atherosclerosis or its complications, and to assess whether demographic or clinical factors affect the development of atherosclerotic disease in a series of patients with PsA attended to in a community hospital. Methods. Fifty-nine patients with PsA who fulfilled the Moll and Wright criteria were recruited from Hospital Xeral-Calde (Lugo, Spain). Patients seen during the period of recruitment who had classic cardiovascular risk factors or had experienced cardiovascular or cerebrovascular events were excluded. Fifty-nine healthy matched controls were also studied. Carotid artery intima-media thickness (IMT) and carotid plaques were measured in the right common carotid artery. The study was performed using high-resolution B-mode ultrasound. Results. Patients with PsA exhibited greater carotid artery IMT than did matched controls (mean ± SD 0.699 ± 0.165 mm versus 0.643 ± 0.111 mm; P = 0.031; difference of means 0.056; 95% confidence interval 0.005-0.108). Adjusted for age, the carotid IMT was correlated with age at the time of PsA diagnosis (partial correlation coefficient [r] = -0.264, P = 0.04), disease duration (r = 0.264, P = 0.04), total cholesterol (r = 0.233, P = 0.01), and low-density lipoprotein cholesterol (r = 0.243, P = 0.01). Conclusion. The present study demonstrates that patients with PsA without cardiovascular risk factors or clinically evident cardiovascular disease have a high prevalence of macrovascular disease in the form of increased carotid artery IMT compared with ethnically matched controls. © 2007, American College of Rheumatology.
Authors & Co-Authors
González-Juanatey, Carlos
Spain, Lugo
Complejo Hospitalario Xeral Calde
Llorca-Díaz, Javier Francisco
Spain, Santander
Universidad de Cantabria
Dierssen-Sotos, Trinidad
Spain, Santander
Universidad de Cantabria
Martin, Javier
Spain, Madrid
Consejo Superior de Investigaciones Científicas
González-Gay, Miguel Ángel
Spain, Lugo
Complejo Hospitalario Xeral Calde
Statistics
Citations: 259
Authors: 5
Affiliations: 3
Identifiers
Doi:
10.1002/art.22884
ISSN:
15290131
Research Areas
Health System And Policy
Noncommunicable Diseases
Study Design
Cross Sectional Study