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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Effect of soybean feeding on experimental carcinogenesis-III. Carcinogenecity of nitrite and dibutylamine in mice: a histopathological study
European Journal of Cancer and Clinical Oncology, Volume 24, No. 3, Year 1988
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Description
The potential carcinogenic effect of nitrosamine precursors, DBA (dibutylamine) and nitrite, was clearly demonstrated pathologically in the liver and bladder of male Swiss albino mice. Benign tumours were induced in the bladder with an incidence of 40%, and hepatomas were detected in the liver in 27% of the cases. The protective effect of soybean and ascorbic acid, added separately to the diet or to the drinking water respectively, was demonstrated by a marked reduction in dysplastic features and absence of tumour in both the liver and the urinary bladder. © 1988.
Authors & Co-Authors
Mokhtar, Nadia Mahmoud
Egypt, Giza
Cairo University
El-Aaser, Abdelbaset Anwer A.
Egypt, Giza
Cairo University
El-Bolkainy, Mohamed Nabil
Egypt, Giza
Cairo University
Ibrahim, Hamdy A.
Egypt, Mansoura
Faculty of Science
El-Din, Nariman Badr
Unknown Affiliation
Moharram, Nagia Z.
Egypt, Giza
Faculty of Science
Statistics
Citations: 40
Authors: 6
Affiliations: 3
Identifiers
Doi:
10.1016/S0277-5379(98)90009-8
ISSN:
02775379
Research Areas
Cancer
Environmental
Study Design
Cohort Study
Participants Gender
Male