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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Prevalence of hepatitis B virus infection among blood donors at the Tamale Teaching Hospital, Ghana (2009)
BMC Research Notes, Volume 5, Article 115, Year 2012
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Description
Background: Despite education and availability of drugs and vaccines, hepatitis B virus (HBV) is still the most common severe liver infection in the world accounting for >1 million annual deaths worldwide. Transfusion of infected blood, unprotected sex and mother to child transmission are 3 key transmission routes of HBV in Ghana. There is high incidence of blood demanding health situations in northern Ghana resulting from anemia, accidents, malnutrition, etc. The higher the demand, the higher the possibility of transmitting HBV through infected blood. The aim of the investigation was to estimate the prevalence of HBV in blood donors which will provide justification for interventions that will help minimize or eliminate HBV infection in Ghana. Findings. We investigated the prevalence of HBV infection among blood donors at Tamale Teaching Hospital. The Wondfo HBsAg test kit was used to determine the concentration of HBsAg in 6,462 (576 voluntary and 5,878 replacement) donors as being 1 ng/ml. 10.79% of voluntary donors and 11.59% of replacement donors were HBsAg+. The 20-29 year group of voluntary donors was >2 times more likely to be HBsAg + than 40-60. Also the 20-29 year category of replacement donors was >4 times as likely to be HBsAg + than 50-69. Conclusions: Risk of infection was age, sex and donor type dependent. The 20-29 year category had the highest prevalence of HBsAg + cases, mostly males residing within the metropolis. © 2012 Dongdem et al; licensee BioMed Central Ltd.
Authors & Co-Authors
Dongdem, Julius Tieroyaare
Ghana, Tamale
University for Development Studies Ghana
Kampo, Sylvanus
Ghana, Tamale
University for Development Studies Ghana
Ghana, Accra
Ministry of Health Ghana
Soyiri, Ireneous N.
Ghana, Accra
University of Ghana
Malaysia, Bandar Sunway
Monash University Malaysia
Asebga, Patrick Nsobila
Ghana, Accra
Ministry of Health Ghana
Ziem, Juventus Benogle
Ghana, Accra
Ministry of Health Ghana
Ghana, Tamale
University for Development Studies Ghana
Sagoe, Kenneth
Ghana, Accra
Ministry of Health Ghana
Statistics
Citations: 61
Authors: 6
Affiliations: 4
Identifiers
Doi:
10.1186/1756-0500-5-115
Research Areas
Food Security
Health System And Policy
Infectious Diseases
Maternal And Child Health
Study Design
Cross Sectional Study
Cohort Study
Study Locations
Ghana