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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
How time to healthy singleton delivery could affect decision-making during infertility treatment: a Delphi consensus
Reproductive BioMedicine Online, Volume 38, No. 1, Year 2019
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Description
Research question: How might time to healthy singleton delivery affect decision-making during infertility treatment? Design: This was a Delphi consensus investigating expert opinion that comprised three steps. In Step 1, 12 experts developed statements. In Step 2, 27 experts (including 12 from Step 1) voted (online survey) on their agreement/disagreement with each statement (providing reasons). Consensus was reached if ≥66% of participants agreed/disagreed. Statements not reaching consensus were revised and the process repeated until consensus was achieved. In Step 3 details of the final agreed statements were communicated. Results: Twelve statements were developed, and consensus (agreement) was reached on all after one round of voting. Conclusions: Time to healthy singleton delivery should be taken into consideration when making decisions related to infertility treatment, and it is important that fertility treatment is provided in a timely manner, avoiding over- or under-treatment. In all subfertile women <40 years old, IVF outcomes could be optimized by performing up to six single-embryo transfers and certain procedures might reduce time to healthy singleton delivery. These procedures include preimplantation genetic testing for aneuploidies, frozen replacement cycles immediately after failed fresh cycles and use of gonadotrophin-releasing hormone antagonists. Finally, the number of oocytes retrieved should be maximized to increase cumulative live birth rate. © 2018 The Authors
Authors & Co-Authors
Bosch, Ernesto A.
Spain, Valencia
Instituto Valenciano de Infertilidad
Yarali, Hakan
Turkey, Ankara
Hacettepe Üniversitesi
Turkey, Ankara
Anatolia Ivf and Women Health Centre
Polyzos, Nikolaos P.
Spain, Barcelona
Hospital Universitari Dexeus
Belgium, Brussels
Vrije Universiteit Brussel
Denmark, Aarhus
Aarhus Universitet
Ubaldi, F. Maria
Italy, Rome
Genera Centre for Reproductive Medicine
García-Velasco, Juan Antonio
Spain, Madrid
Instituto de Investigación Sanitaria Del Hospital Universitario la Paz
Longobardi, Salvatore
Germany, Darmstadt
Merck Kgaa
D'Hooghe, Thomas Maria
Belgium, Leuven
Ku Leuven
Denmark, Aarhus
Fakultetet Health
Humaidan, Peter Samir Heskjær
Denmark, Aarhus
Aarhus Universitet
Denmark, Aarhus
Fakultetet Health
Statistics
Citations: 13
Authors: 8
Affiliations: 15
Identifiers
Doi:
10.1016/j.rbmo.2018.09.019
ISSN:
14726483
Research Areas
Genetics And Genomics
Sexual And Reproductive Health
Study Design
Cross Sectional Study
Study Approach
Quantitative
Participants Gender
Female