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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Distribution of persistent organochlorine contaminants in infertile patients from Tanzania and Germany
Journal of Assisted Reproduction and Genetics, Volume 23, No. 9-10, Year 2006
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Description
Purpose: To test whether environmental pollutants could affect fertility in humans. Methods: 31 women and 16 men from Tanzania and 21 couples from Germany were included (n=89). Pesticides and polychlorinated biphenyls were measured in serum, follicular fluid or seminal plasma by gaschromatography and related to sperm quality and pregnancy rates. Results: Higher concentrations of DDT+DDE and dieldrin in Tanzania and higher concentrations of PCBs in Germany and in men were detected. All compounds showed higher concentrations in serum and lowest concentrations in seminal plasma. A lower pregnancy rate in German women with high serum concentrations of DDT+DDE was observed. The toxins had no impact on sperm quality. Conclusions: The distribution of toxins between agricultural and industrial countries is different. Seminal plasma seems to be inert against chemicals. In patients with high serum concentrations of DDT and DDE pregnancy rates were impaired. © 2006 Springer Science+Business Media, LLC.
Authors & Co-Authors
Weiss, Juergen Michael
Germany, Lubeck
Universitätsklinikum Schleswig-holstein Campus Lübeck
Bauer, Ottmar
Germany, Lubeck
Universitätsklinikum Schleswig-holstein Campus Lübeck
Blüthgen, Albrecht
Germany, Karlsruhe
Max Rubner-institut, Germany
Ludwig, Annika Kristin
Germany, Lubeck
Universitätsklinikum Schleswig-holstein Campus Lübeck
Vollersen, Elke
Germany, Lubeck
Universitätsklinikum Schleswig-holstein Campus Lübeck
Kaisi, Malise
Tanzania, Dar es Salaam
University of Dar es Salaam
Al-Hasani, Safaa A.
Germany, Lubeck
Universitätsklinikum Schleswig-holstein Campus Lübeck
Diedrich, Klaus
Germany, Lubeck
Universitätsklinikum Schleswig-holstein Campus Lübeck
Ludwig, Michael
Germany, Hamburg
Endokrinologikum Hamburg
Statistics
Citations: 55
Authors: 9
Affiliations: 4
Identifiers
Doi:
10.1007/s10815-006-9069-6
ISSN:
10580468
Research Areas
Maternal And Child Health
Sexual And Reproductive Health
Study Locations
Tanzania
Participants Gender
Male
Female