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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
The Status of Adolescent Testing and Treatment in PEPFAR-Supported Programs, October 2017 to September 2020
Journal of Acquired Immune Deficiency Syndromes, Volume 93, No. 1, Year 2023
Notification
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Description
Background:Adolescents have poorer outcomes across the HIV cascade compared with adults. We aimed to assess progress in HIV case finding, antiretroviral treatment (ART), viral load coverage (VLC), and viral load suppression (VLS) among adolescents enrolled in the US President's Emergency Plan for AIDS Relief (PEPFAR)-supported programs over a 3-year period that included the beginning of the COVID-19 pandemic.Methods:We analyzed PEPFAR program data in 28 countries/regions for adolescents aged 10-19 years between year 1 (October 2017to September 2018), year 2 (October 2018 to September 2019), and year 3 (October 2019 to September 2020). We calculated the number and percent change for HIV tests, HIV-positive tests, and total number on ART. Calculated indicators included positivity, percent of positives newly initiated on ART (ART linkage), VLC (percent of ART patients on ART for ≥6 months with a documented viral load result within the past 12 months), and VLS (percent of viral load tests with <1000 copies/mL).Results:Between years 1 and 3, the number of HIV tests conducted decreased by 44.2%, with a 29.1% decrease in the number of positive tests. Positivity increased from 1.3%-1.6%. The number of adolescents receiving ART increased by 10.4%. In addition, ART linkage increased (77.8%-86.7%) as did VLC (69.4%-79.4%) and VLS (72.8%-81.5%).Conclusions:Our findings demonstrate PEPFAR's success in increasing the adolescent treatment cohort. We identified ongoing gaps in adolescent case finding, linkage, VLC, and VLS that could be addressed with a strategic mix of testing strategies, optimal ART regimens, and adolescent-focused service delivery models. © Copyright 2023 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited.
Authors & Co-Authors
Hrapcak, Susan
United States, Atlanta
Centers for Disease Control and Prevention
Hast, Marisa A.
United States, Atlanta
Centers for Disease Control and Prevention
Okegbe, Tishina C.
United States, Washington, D.c.
United States Agency for International Development
Gross, Jessica M.
United States, Atlanta
Centers for Disease Control and Prevention
Patel, Monita R.
United States, Atlanta
Centers for Disease Control and Prevention
Wolf, Hilary T.
Unknown Affiliation
Siberry, George Kelly
United States, Washington, D.c.
United States Agency for International Development
Lee, Lana
United States, Washington, D.c.
United States Agency for International Development
Agaba, Patricia A.
United States, Silver Spring
Walter Reed Army Institute of Research
United States, Rockville
Hjf
Carpenter, Deborah
United States, Atlanta
Centers for Disease Control and Prevention
Rivadeneira, Emilia D.
United States, Atlanta
Centers for Disease Control and Prevention
Neto, Zoraima
Unknown Affiliation
Makwepa, Daphne K.
Unknown Affiliation
Dokubo, Emily Kainne
Unknown Affiliation
Mayer, Magdalene Mange
Unknown Affiliation
Shang, Judith D.
Unknown Affiliation
Wright, Janell
Unknown Affiliation
Prao, Aka K.
Unknown Affiliation
Longuma, Henri O.
Unknown Affiliation
Kabwe, Constantin
Unknown Affiliation
Mndzebele, Phumzile
Unknown Affiliation
Teferi, Wondimu
Unknown Affiliation
Allam, Ramesh Reddy
Unknown Affiliation
Mutisya, Immaculate N.
Unknown Affiliation
Nyabiage, Lennah
Unknown Affiliation
Ts'Oeu, Mamorapeli
Unknown Affiliation
Kayira, Dumbani
Unknown Affiliation
Deus, Maria Inés
Unknown Affiliation
Battey, Katherine A.
Unknown Affiliation
Ene, Uzoma
Unknown Affiliation
Musoni, Canisious
Unknown Affiliation
Kindra, Gurpreet
Unknown Affiliation
Mondi, John
Unknown Affiliation
Machage, Edward M.
Unknown Affiliation
Nazziwa, Esther R.
Unknown Affiliation
Barzilay, Ezra J.
Unknown Affiliation
Musokotwane, Kebby
Unknown Affiliation
Maphosa, Talent
Unknown Affiliation
Baramperanye, Evelyne
Unknown Affiliation
Nzima, Valery N.
Unknown Affiliation
Tilahun, Tsegaye
Unknown Affiliation
Zomba, Gerald
Unknown Affiliation
Maguwu, Onesimo
Unknown Affiliation
Akao, Juliette N.
Unknown Affiliation
Njeru, Dorothy
Unknown Affiliation
Adamu, Yakubu
Unknown Affiliation
Mwambona, Janet T.
Unknown Affiliation
Birabwa, Estella
Unknown Affiliation
Statistics
Authors: 48
Affiliations: 5
Identifiers
Doi:
10.1097/QAI.0000000000003166
ISSN:
15254135
Research Areas
Covid
Health System And Policy
Infectious Diseases
Study Design
Cohort Study