EBV‐positive Burkitt's lymphoma from algeria, with a three‐way rearrangement involving chromosomes 2, 8 and 9

Burkitt's lymphoma was diagnosed in a male Algerian child presenting with abdominal and jaw tumours. Viral studies revealed that this non‐endemic case was associated with the Epstein‐Barr virus. Cytogenetic examination of tumour cells showed a complex three‐way rearrangement involving chromosomes 2, 8 and 9. Our report indicates that, in Burkitt's lymphoma, not only simple but also complex translocations involving chromosome 8 may arise. This finding in a North African case emphasizes the need for more detailed study of the clinical, virological and cytogenetic features of Burkitt's lymphoma throughout the world. Copyright © 1981 Wiley‐Liss, Inc., A Wiley Company