Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Net benefits: A multicountry analysis of observational data examining associations between insecticide-treated mosquito nets and health outcomes
PLoS Medicine, Volume 8, No. 9, Article e1001091, Year 2011
Notification
URL copied to clipboard!
Description
Background: Several sub-Saharan African countries have rapidly scaled up the number of households that own insecticide-treated mosquito nets (ITNs). Although the efficacy of ITNs in trials has been shown, evidence on their impact under routine conditions is limited to a few countries and the extent to which the scale-up of ITNs has improved population health remains uncertain. Methods and Findings: We used matched logistic regression to assess the individual-level association between household ITN ownership or use in children under 5 years of age and the prevalence of parasitemia among children using six malaria indicator surveys (MIS) and one demographic and health survey. We used Cox proportional hazards models to assess the relationship between ITN household ownership and child mortality using 29 demographic and health surveys. The pooled relative reduction in parasitemia prevalence from random effects meta-analysis associated with household ownership of at least one ITN was 20% (95% confidence interval [CI] 3%-35%; I2 = 73.5%, p<0.01 for I2 value). Sleeping under an ITN was associated with a pooled relative reduction in parasitemia prevalence in children of 24% (95% CI 1%-42%; I2 = 79.5%, p<0.001 for I2 value). Ownership of at least one ITN was associated with a pooled relative reduction in mortality between 1 month and 5 years of age of 23% (95% CI 13-31%; I2 = 25.6%, p>0.05 for I2 value). Conclusions: Our findings across a number of sub-Saharan African countries were highly consistent with results from previous clinical trials. These findings suggest that the recent scale-up in ITN coverage has likely been accompanied by significant reductions in child mortality and that additional health gains could be achieved with further increases in ITN coverage in populations at risk of malaria. Please see later in the article for the Editors' Summary. © 2011 Lim et al.
Authors & Co-Authors
Lim, Stephen S.
United States, Seattle
University of Washington
Fullman, Nancy
United States, Seattle
University of Washington
Stokes, Andrew C.
United States, Philadelphia
University of Pennsylvania
Ravishankar, Nirmala
United States, Cambridge
Abt Associates, Inc.
Masiye, Felix
Zambia, Lusaka
University of Zambia
Murray, Christopher J.L.
United States, Seattle
University of Washington
Gakidou, Emmanuela E.
United States, Seattle
University of Washington
Statistics
Citations: 166
Authors: 7
Affiliations: 4
Identifiers
Doi:
10.1371/journal.pmed.1001091
ISSN:
15491277
e-ISSN:
15491676
Research Areas
Health System And Policy
Infectious Diseases
Maternal And Child Health
Study Design
Cross Sectional Study
Study Approach
Quantitative
Systematic review