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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Comparison of central pressure estimates obtained from SphygmoCor, Omron HEM-9000AI and carotid applanation tonometry
Journal of Hypertension, Volume 29, No. 6, Year 2011
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Description
Background: The Omron HEM-9000AI is the first automated tonometer to provide an estimate of central SBP (cSBP), which is considered to be more predictive of cardiovascular events than brachial pressure. However, considerable differences between the cSBP estimate of Omron and that of SphygmoCor have been reported, but not explained. This study assesses the sources of differences between both cSBP estimates and provides a handle on which estimate is closest to reality. METHOD: For this purpose, aortic cSBP derived from calibrated carotid SBP was used as device- and algorithm- independent reference. Radial, brachial and carotid applanation tonometry were performed in 143 black South Africans, aged 39-91 years. Each individual was measured with an Omron HEM-9000AI and a SphygmoCor. Results: When using both devices as advocated by their manufacturers, the corresponding cSBP estimates correlated strongly (r = 0.99, P < 0.001), but the Omron estimate was 18.8 (4.3) mmHg higher than the SphygmoCor estimate. Aortic SBP was in between both estimates: 11.7 (5.5) mmHg lower than cSBP-Omron and 7.1 (5.0) mmHg higher than cSBP-SphygmoCor. Alternative calibration of the radial SphygmoCor-curves with radial instead of brachial pressures yielded a cSBP that was 3.0 (4.2) mmHg lower than aortic SBP. The shape of the recorded pressure waves was similar in both devices: less than 5% of the observed cSBP difference was caused by differences in wave shape. Conclusion: The results from this study demonstrate that the considerable difference between the central pressure estimates of Omron HEM-9000AI and SphygmoCor is due to algorithm differences, and suggest that the overestimation by Omron HEM-9000AI is larger than the underestimation by SphygmoCor. © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins.
Authors & Co-Authors
Kips, Jan G.
Belgium, Ghent
Heymans Institute of Pharmacology
Belgium, Ghent
Universiteit Gent
Schutte, Aletta E.
South Africa, Potchefstroom
North-west University
Vermeersch, Sebastian J.
Belgium, Ghent
Heymans Institute of Pharmacology
Belgium, Ghent
Universiteit Gent
Huisman, Hugo Willem
South Africa, Potchefstroom
North-west University
van Rooyen, Johannes Marthinus
South Africa, Potchefstroom
North-west University
Glyn, Matthew Colin P.
South Africa, Potchefstroom
North-west University
Fourie, Carla M. T. Maria Theresia
South Africa, Potchefstroom
North-west University
Malan, Leoné
South Africa, Potchefstroom
North-west University
Schutte, Rudolph
South Africa, Potchefstroom
North-west University
van Bortel, Luc M.A.B.
Belgium, Ghent
Heymans Institute of Pharmacology
Segers, Patrick F.
Belgium, Ghent
Universiteit Gent
Statistics
Citations: 66
Authors: 11
Affiliations: 3
Identifiers
Doi:
10.1097/HJH.0b013e328346a3bc
ISSN:
02636352
Research Areas
Noncommunicable Diseases