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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Association between physical activity and brain health in older adults
Neurobiology of Aging, Volume 34, No. 1, Year 2013
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Description
In the present cross-sectional study, we examined physical activity (PA) and its possible association with cognitive skills and brain structure in 331 cognitively healthy elderly. Based on the number of self-reported light and hard activities for at least 30 minutes per week, participants were assigned to 4 groups representing different levels of PA. The cognitive skills were assessed by the Mini Mental State Examination score, a verbal fluency task, and the Trail-making test as a measure of visuospatial orientation ability. Participants also underwent a magnetic resonance imaging of the brain. Multiple regression analysis revealed that greater PA was associated with a shorter time to complete the Trail-making test, and higher levels of verbal fluency. Further, the level of self-reported PA was positively correlated with brain volume, white matter, as well as a parietal lobe gray matter volume, situated bilaterally at the precuneus. These present cross-sectional results indicate that PA is a lifestyle factor that is linked to brain structure and function in late life. © 2013 Elsevier Inc.
Authors & Co-Authors
Benedict, Christian
Sweden, Uppsala
Uppsala Universitet
Brooks, Samantha Jane
Sweden, Uppsala
Uppsala Universitet
Kullberg, Joel
Sweden, Uppsala
Uppsala Universitet
Kilander, Lena
Sweden, Uppsala
Uppsala Universitet
Larsson, Elna Marie
Sweden, Uppsala
Uppsala Universitet
Johansson, Lars O.M.
Sweden, Uppsala
Uppsala Universitet
Åhlström, Håkan K.
Sweden, Uppsala
Uppsala Universitet
Lind, Lars L.
Sweden, Uppsala
Uppsala Universitet
Schiöth, Helgi Birgir
Sweden, Uppsala
Uppsala Universitet
Statistics
Citations: 121
Authors: 9
Affiliations: 1
Identifiers
Doi:
10.1016/j.neurobiolaging.2012.04.013
ISSN:
15581497
Study Design
Cross Sectional Study
Study Approach
Quantitative