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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
veterinary
Vaccination of Tunisian dogs with the lyophilised SAG2 oral rabies vaccine incorporated into the DBL2 dog bait
Veterinary Research, Volume 30, No. 6, Year 1999
Notification
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Description
The protective effect of the lyophilised SAG2 oral vaccine bait DBL2, already demonstrated on laboratory dogs, needed to be verified on common Tunisian dogs. Seven Tunisian dogs consumed totally or partially one DBL2 bait containing 108.3 TCID50 of the highly attenuated rabies vaccine strain, SAG2. Five of the seven vaccinated animals survived a challenge administered 33 days later with a Tunisian canine street rabies virus to which five of the six controls that were not vaccinated and had no specific antibodies succumbed. The partial or total consumption of a single DBL2 bait thus conferred a protective immune response similar to that observed in laboratory dogs to dogs of poor health status. The sero-antibody response was, however, weak: only two vaccinated dogs exhibited a significant neutralising antibody response after vaccination and before the challenge, and four after the challenge. © Inra/Elsevier, Paris.
Authors & Co-Authors
Hammami, Salah
Tunisia, Tunis
Institut de Recherche Vétérinaire de Tunis
Schumacher, Carolin L.
France, Carros
Virbac sa
Cliquet, Florence
France, Maisons-alfort
Afssa Agence Française de Sécurité Sanitaire Des Aliments
Tlatli, Aida
Tunisia, Tunis
Institut de Recherche Vétérinaire de Tunis
Aubert, A.
France, Carros
Virbac sa
Aubert, Michel
France, Maisons-alfort
Afssa Agence Française de Sécurité Sanitaire Des Aliments
Statistics
Citations: 6
Authors: 6
Affiliations: 3
Identifiers
ISSN:
09284249
Research Areas
Health System And Policy