Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Seroprevalence of hepatitis B in a cohort of HIV-infected children and adults in Swaziland
International Journal of STD and AIDS, Volume 24, No. 7, Year 2013
Notification
URL copied to clipboard!
Description
Hepatitis B virus (HBV) is an important co-morbidity in the HIV epidemic. A retrospective chart review was performed of HIV-infected patients with no previous antiretroviral history enrolled in a Swaziland clinic from January 2009 to May 2011. The seroprevalence of HBV surface antigen (HBsAg) was calculated and the data were analyzed using Mann-Whitney U and Fisher's exact tests. A total of 1282 patients were included in analysis. Five hundred were children aged <15 years. Overall HBsAg seroprevalence was 3.7% (1.4% of children and 5.1% of adults). Prevalence in under-5s was low (0.4%). Among adult women and men, prevalence was 4.2% and 9.8%, respectively (P = 0.022). Median alanine aminotransferase level was 19 U/L in the HBsAg-negative adults and 25 U/L in the HBsAg-positive adults (P = 0.005). Given the number of patients found to be HBsAg-positive, especially among adults, it is important for antiretroviral programmes to consider universal screening and strategically utilize medications that have been found effective in treating both HBV and HIV. © The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.
Authors & Co-Authors
Dziuban, Eric J.
United States, Houston
Baylor College of Medicine International Pediatric Aids Initiative at Texas Children's Hospital
United States, Houston
Baylor College of Medicine
Marton, Stephanie A.
United States, Houston
Baylor College of Medicine
Hughey, Allison B.
United States, Houston
Baylor College of Medicine International Pediatric Aids Initiative at Texas Children's Hospital
Mbingo, T. L.
Swaziland, Mbabane
Baylor College of Medicine Children's Foundation-swaziland
Draper, Heather R.
United States, Houston
Baylor College of Medicine International Pediatric Aids Initiative at Texas Children's Hospital
United States, Houston
Baylor College of Medicine
Schutze, Gordon E.
United States, Houston
Baylor College of Medicine International Pediatric Aids Initiative at Texas Children's Hospital
United States, Houston
Baylor College of Medicine
Statistics
Citations: 12
Authors: 6
Affiliations: 3
Identifiers
Doi:
10.1177/0956462413476274
ISSN:
09564624
Research Areas
Health System And Policy
Infectious Diseases
Maternal And Child Health
Study Design
Cross Sectional Study
Cohort Study
Study Locations
Eswatini
Participants Gender
Male
Female