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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Clinical and electrophysiological profile of brugada syndrome in the tunisian population
PACE - Pacing and Clinical Electrophysiology, Volume 34, No. 1, Year 2011
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Description
Background: Most clinical studies of the clinical profile of Brugada syndrome (BS) have been conducted in either Asia, Europe, or America and their applicability to North African populations is largely unknown. The aim of the study was to analyze the clinical profile of BS in Tunisian patients. Methods: The clinical and follow-up data of 24 patients (22 men, mean age: 40.8 ± 13.7 years) were collected since 2002. Baseline characteristics, morbidity, and mortality data were obtained from medical records. Results: One patient (4.16%) survived sudden cardiac death (SCD), four patients (16.3%) had syncope, and 19 patients (79.1%) were asymptomatic. Eleven patients (45.8%) had a family history of SCD. Twenty patients showed a spontaneous coved-type ST-segment elevation on electrocardiogram and after medical challenge on the four remnants. An electrophysiological study was performed in 15 of 24 patients (62.5%), during which ventricular fibrillation was induced in six patients (40%); three of the six patients were previously asymptomatic. An implantable cardioverter defibrillator (ICD) was implanted in 14 patients (58.3%). After a mean follow-up of 26 ± 21 months, one patient died from a noncardiac cause and one patient (with a history of aborted SCD) received an appropriate shock from his ICD. None of the asymptomatic and noninducible patients experienced a cardiac event. Conclusions: BS is present in the North African population and is probably under-recognized. Tunisian patients with BS share with their western and Asiatic counterparts similar clinical profile. (PACE 2011; 47-53) ©2010 Wiley Periodicals, Inc.
Authors & Co-Authors
Ouali, Sana
Tunisia, Sousse
Chu Sahloul
Boughzéla, Essia
Tunisia, Sousse
Chu Sahloul
Haggui, Abdeddayem
Tunisia, Tunis
Université de Tunis el Manar, Hôpital Militaire de Tunis
Haouala, Habib
Tunisia, Tunis
Université de Tunis el Manar, Hôpital Militaire de Tunis
Battikh, Kaïs
Tunisia, Tunis
Université de Tunis el Manar, Hôpital Habib Thameur
Ameur, Youssef Ben
Tunisia, Tunis
Université de Tunis el Manar, Hôpital Habib Thameur
Kraïem, Sondos
Tunisia, Tunis
Université de Tunis el Manar, Hôpital Habib Thameur
Krichen, Salma
Tunisia, Sfax
Chu Hedi-chaker
Hentati, Mourad
Tunisia, Sfax
Chu Hedi-chaker
Kammoun, Samir
Tunisia, Sfax
Chu Hedi-chaker
Statistics
Citations: 13
Authors: 10
Affiliations: 4
Identifiers
Doi:
10.1111/j.1540-8159.2010.02890.x
ISSN:
01478389
e-ISSN:
15408159
Research Areas
Health System And Policy
Noncommunicable Diseases
Study Design
Cross Sectional Study
Cohort Study
Participants Gender
Male