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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
chemical engineering
Magnetic properties of Zn-substituted MnFe
2
O
4
nanoparticles synthesized in polyol as potential heating agents for hyperthermia. Evaluation of their toxicity on endothelial cells
Chemistry of Materials, Volume 22, No. 19, Year 2010
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Description
Stoichiometric Mn0.2Zn0.8Fe2O4 monodisperse nanoparticles were prepared by the so-called polyol method. The variation of magnetization as a function of magnetic field H (up to ±50 kOe) and temperature (5-320 K) were investigated, for zero-field-cooled (ZFC) and field-cooled (FC) conditions on freshly produced powder. The T variation of the low-field (H = 200 Oe) magnetic susceptibility is characteristic of superparamagnets with a blocking temperature below room temperature. The H variation of the low temperature (T = 5 K) magnetization exhibits a hysteresis loop. The coercivity is weak, about 0.2-0.3 kOe, which is typical of soft-ferrimagnetic materials. The 0 K saturation magnetization and the Curie temperature are found to be 98 emu.g-1 and 360 K, respectively. The magnetic properties of the particles are discussed in relation with their chemical composition and their cation distribution in the opportunity of using them as heating mediators for hyperthermia application in cancer therapy. In this aim, the toxicity of the particles was also evaluated by viability assays on human umbilical vein endothelial cells (HUVEC). © 2010 American Chemical Society.
Authors & Co-Authors
Beji, Zyed
France, Paris
Université Paris Cité
Tunisia, Tunis
University of Carthage
Hanini, Amel
France, Paris
Université Paris Cité
France, Paris
Institut Cochin
France, Paris
Inserm
Smiri, Leila Samia
Tunisia, Tunis
University of Carthage
Gavard, Julie
France, Paris
Institut Cochin
France, Paris
Inserm
Kacem, Kamel
Tunisia, Tunis
University of Carthage
Villain, F.
France, Paris
Sorbonne Université
Grenèche, J. M.
France, Le Mans
Le Mans Université
Chau, François
France, Paris
Université Paris Cité
Ammar-Merah, Souad
France, Paris
Université Paris Cité
Statistics
Citations: 102
Authors: 9
Affiliations: 6
Identifiers
Doi:
10.1021/cm1001708
ISSN:
08974756
e-ISSN:
15205002
Research Areas
Cancer
Study Approach
Qualitative