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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Primary cancer of the liver in Kenyan children
British Journal of Cancer, Volume 36, No. 6, Year 1977
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Description
In 9 years in Kenya, 34 examples of primary liver cancer wer diagnosed in patients in the first two decades of life. This represents 4.7% of all liver cancers during this period. The larger proportion (29) were hepatocellular carcinoma. In the second decade, there was a notable association with macronodular cirrhosis. Analogy with experimental work suggests that cells in mitotic cycle may be more vulnerable to the effect of environmental carcinogens. Five examples of hepatoblastoma were identified at ages from 2 months to 14 years, none showed the features of "mixed" tumours. The ratio of hepatoblastoma to hepatocellular carcinoma was the reverse of that found in other large series of juvenile hepatic tumours. The histopathological features of these tumours are described and problems of their classification are discussed. © 1977, The British Empire Cancer Campaign for Research. All rights reserved.
Authors & Co-Authors
Cameron, Helen Mc D.
Kenya, Nairobi
University of Nairobi
United Kingdom, Edinburgh
The University of Edinburgh
Warwick, Gerald P.
Kenya, Nairobi
University of Nairobi
Switzerland, Geneve
Internatioinal Union Against Cancer
Statistics
Citations: 24
Authors: 2
Affiliations: 3
Identifiers
Doi:
10.1038/bjc.1977.264
e-ISSN:
15321827
Research Areas
Cancer
Maternal And Child Health
Study Locations
Kenya