Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Twelve-year follow-up study of hepatitis B immunization of Senegalese infants
Journal of Hepatology, Volume 21, No. 2, Year 1994
Notification
URL copied to clipboard!
Description
Numerous studies have documented the efficacy and safety of plasma-derived and recombinant hepatitis B vaccines. However, little is known about the long-term protection of hepatitis B vaccine, when anti-HBs declines to low or undetectable levels. This study reports results from a 9-12-year period follow up of infants immunized against hepatitis B in Senegal. At the end of the follow-up period anti-HBs were detected in 81% of children who received a booster dose at school age and in 68% of those who did not. HBsAg was detected in 19% of infants from the control group compared to only 2% of immunized infants, corresponding to a protective efficacy of 88%. The results show that long-term protection against HBsAg carriage of hepatitis B vaccination is very high and that a booster dose at school age does not significantly increase this protection. © 1994 Journal of Hepatology.
Authors & Co-Authors
Coursaget, Pierre L.
Unknown Affiliation
Leboulleux, Didier
France, Tours
Université de Tours
Soumare ́, Masserigné L.
France, Tours
Université de Tours
Le Cann, Pierre
Unknown Affiliation
Yvonnet, Bernard
Unknown Affiliation
Chiron, Jeanpaul
Unknown Affiliation
Coll-Seck, Anna Marie
France, Tours
Université de Tours
Diop-Mar, Ibrahima
France, Tours
Université de Tours
Statistics
Citations: 110
Authors: 8
Affiliations: 1
Identifiers
Doi:
10.1016/S0168-8278(05)80404-0
ISSN:
01688278
Research Areas
Infectious Diseases
Maternal And Child Health
Study Design
Randomised Control Trial
Cohort Study
Study Locations
Senegal