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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Determinants of optimal adherence over time to antiretroviral therapy amongst hiv positive adults in south africa: A longitudinal study
AIDS and Behavior, Volume 15, No. 7, Year 2011
Notification
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Description
Highly active antiretroviral therapy (HAART) requires strict adherence to achieve optimal clinical and survival benefits. A study was done to explore the factors affecting HAART adherence among HIV positive adults by reviewing routinely collected patient information in the Centre for the AIDS Programme of Research in South Africa's (CAPRISA) AIDS Treatment Programme. Records of 688 patients enrolled between 2004 and 2006 were analysed. Patients were considered adherent if they had taken at least 95% of their prescribed drugs. Generalized estimating equations were used to analyse the data. The results showed that HAART adherence increased over time, however, the rate of increase differed by some of the socio-demographic and behavioural characteristics of the patients. For instance, HAART adherence increased in both urban and rural treatment sites over time, but the rate of increase was higher in the rural site. This helped identify sub-populations, such as the urban population, that required ongoing adherence counseling. © Springer Science+Business Media, LLC 2010.
Authors & Co-Authors
Maqutu, Dikokole
South Africa, Scottsville
Ukzn
South Africa, Congella
Centre for the Aids Programme of Research in South Africa
Zewotir, Temesgen T.
South Africa, Scottsville
Ukzn
North, Delia E.
South Africa, Scottsville
Ukzn
Naidoo, Kogieleum L.
South Africa, Congella
Centre for the Aids Programme of Research in South Africa
Grobler, Anneke C.
South Africa, Congella
Centre for the Aids Programme of Research in South Africa
Statistics
Citations: 49
Authors: 5
Affiliations: 2
Identifiers
Doi:
10.1007/s10461-010-9688-x
ISSN:
10907165
Research Areas
Health System And Policy
Infectious Diseases
Study Design
Cross Sectional Study
Cohort Study
Study Approach
Quantitative
Study Locations
South Africa