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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Serological evidence of dengue fever among refugees, Hargeysa, Somalia
Journal of Medical Virology, Volume 29, No. 2, Year 1989
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Description
Epidemics of a malaria‐like illness affected several thousand residents of the Dam Camp, a refugee camp near Hargeysa in Somalia, during 1985, 1986, and 1987. The disease was characterized by fever, chills, sweats, headache, back and joint pains for as long as 10 days in some patients. Blood smears from acutely ill patients were negative for malaria. Of 28 acute and 10 convalescent sera tested by the indirect fluorescent antibody (IFA) and by the hemagglutination inhibition (HI) tests, all were negative for antibody to Rift Valley fever, Crimean‐Congo hemorrhagic fever, Sindbis, Chikungunya, yellow fever, and Zika viruses. However, antibody reactive to dengue 2 virus was detected by the IFA test in 39% (15/38), and 11 of 29 (38%) of the same sera were antibody positive by the HI test. Also, IgG antibody reactive to dengue 2 was demonstrated in 60% (17/28) of the same sera by the enzyme immunoassay (EIA), and 14% (4/28) were positive for IgM antibody. Of ten patients for which acute and convalescent sera were available, two developed four fold or greater rises in antibody titer evidencing infection. These data suggested that dengue virus may have been the cause of the epidemic among the Dam Camp refugees. Copyright © 1989 Wiley‐Liss, Inc., A Wiley Company
Authors & Co-Authors
Botros, Boulos A.M.
Egypt, Cairo
U.s. Naval Medical Research Unit No. 3, Egypt
Watts, Douglas M.
Egypt, Cairo
U.s. Naval Medical Research Unit No. 3, Egypt
Soliman, Atef Kamal
Egypt, Cairo
U.s. Naval Medical Research Unit No. 3, Egypt
Salib, Adel W.
Egypt, Cairo
U.s. Naval Medical Research Unit No. 3, Egypt
Moussa, Mahmoud I.
Egypt, Cairo
U.s. Naval Medical Research Unit No. 3, Egypt
Mursal, H.
Somalia, Mogadishu
Ministry of Health
Douglas, C.
Somalia, Mogadishu
Ministry of Health
Farah, M.
Somalia, Mogadishu
Ministry of Health
Statistics
Citations: 35
Authors: 8
Affiliations: 2
Identifiers
Doi:
10.1002/jmv.1890290202
ISSN:
01466615
e-ISSN:
10969071
Research Areas
Infectious Diseases
Study Locations
Congo
Somalia