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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Prevalence of chronic kidney disease in diabetic adult out-patients in Tanzania
BMC Nephrology, Volume 14, No. 1, Article 183, Year 2013
Notification
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Description
Background: The number of adults with diabetes mellitus is increasing worldwide, particularly in Asia and Africa. In sub-Saharan Africa, renal complications of diabetes may go unrecognized due to limited diagnostic resources. The prevalence of chronic kidney disease (CKD) among adult diabetics in sub-Saharan Africa has not been well described. Methods. This study was conducted at the diabetes mellitus clinic of Bugando Medical Centre in Mwanza, Tanzania. A total 369 consecutive adult diabetic patients were enrolled and interviewed. Each patient provided a urine sample for microalbuminuria and proteinuria and a blood sample for serum creatinine level. Estimated glomerular filtration rate (eGFR) was calculated using the Cockroft-Gault equation. CKD was staged according to the Kidney Disease Improving Global Outcomes system. Results: A total of 309 (83.7%) study participants had CKD; 295 (80.0%) had significant albuminuria and 91 (24.7%) had eGFR < 60 ml/min. None of these patients were aware of their renal disease, and only 5 (1.3%) had a diagnosis of diabetic nephropathy recorded in their file. Older age was significantly associated with CKD in this population [OR 1.03, p = 0.03, 95%CI (1.00-1.05)]. Conclusions: Chronic kidney disease is highly prevalent among adult diabetic outpatients attending our clinic in Tanzania, but is usually undiagnosed. Nearly of patients had an eGFR low enough to require dose adjustment of diabetic medications. More diagnostic resources are needed for CKD screening among adults in Tanzania in order to slow progression and prevent complications. © 2013 Janmohamed et al.; licensee BioMed Central Ltd.
Authors & Co-Authors
Janmohamed, Mubarakali N.
Tanzania, Mwanza
Bugando Medical Centre
Kalluvya, Samuel Elias
Tanzania, Mwanza
Bugando Medical Centre
Mueller, Andreas
Germany, Wurzburg
Medical Mission Hospital
Kabangila, Rodrick
Tanzania, Mwanza
Bugando Medical Centre
Smart, Luke R.
Tanzania, Mwanza
Bugando Medical Centre
United States, New York
Weill Cornell Medicine
Downs, Jennifer Alzos
Tanzania, Mwanza
Bugando Medical Centre
United States, New York
Weill Cornell Medicine
Peck, Robert N.
Tanzania, Mwanza
Bugando Medical Centre
United States, New York
Weill Cornell Medicine
Statistics
Citations: 28
Authors: 7
Affiliations: 3
Identifiers
Doi:
10.1186/1471-2369-14-183
e-ISSN:
14712369
Research Areas
Health System And Policy
Noncommunicable Diseases
Study Design
Cross Sectional Study
Study Locations
Tanzania