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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Geographical and social influences on genetic diversity within the Egyptian population: Analyses of Alu insertion polymorphisms
Annals of Human Biology, Volume 41, No. 1, Year 2014
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Description
Background: The geographical location of Egypt at the crossroads of several major cultural areas between North Africa and the Middle East has contributed to its population history. Aim: To analyse the genetic structure of the population living in two geographical parts of Egypt. Subjects and methods: A sample of 112 Egyptians from the North African part of Egypt (Ismailia sample) and a sample of 52 Egyptians from the Asian part Sinai, have been analysed using 10 Alu insertion polymorphisms. Results: The results of the present study showed a significant genetic difference between the Sinai and Ismailia samples. The latter showed an evident genetic affinity with North African populations; whereas the Sinai sample was found to be genetically closer to the Middle East populations. The Sinai sample showed a low average heterozygosity, unlike that found in the Ismailia sample. Conclusion: This study provides new insights into the genetic structure of the Egyptian population living in a land bridge between Africa and Asia. Results suggest a genetic discontinuity between the Sinai population and that of the North African part of Egypt. This discontinuity would have been maintained thanks to geo-climatic and social factors. © 2014 Informa UK Ltd.
Authors & Co-Authors
Salem, Abdel Halim
Bahrain, Manama
Arabian Gulf University
Egypt, Ismailia
Faculty of Medicine
Bahri, Raoudha
Tunisia, Monastir
Université de Monastir
Jarjanazi, Hamdi
Canada, Toronto
Ontario Ministry of the Environment
Chaabani, Hassen
Tunisia, Monastir
Université de Monastir
Statistics
Citations: 4
Authors: 4
Affiliations: 4
Identifiers
Doi:
10.3109/03014460.2013.826734
e-ISSN:
14645033
Research Areas
Environmental
Genetics And Genomics
Study Design
Cross Sectional Study
Study Locations
Multi-countries
Egypt