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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Many vaginal microbicide trial participants acknowledged they had misreported sensitive sexual behavior in face-to-face interviews
Journal of Clinical Epidemiology, Volume 62, No. 7, Year 2009
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Description
Objective: We investigated whether participants in a phase II randomized clinical trial of a candidate vaginal microbicide ever intentionally misled interviewers. Study Design and Setting: We used audio computer-assisted self-interviews (ACASI) to ask the South African women (n = 132) participating in the trial about the accuracy of self-reported data collected during face-to-face interviews. The trial protocol recommended that women use their assigned gel (active microbicide or placebo) with condoms during each vaginal sex act. Results: Nearly four-fifths of participants (n = 104, 79%) reported that they had misinformed trial interviewers at least once. Motivations included politeness (n = 45, 34% of ACASI participants) to avoid criticism or seek praise (n = 32, 24%), and embarrassment (n = 24, 18%). Participants acknowledged misreporting eligibility characteristics to enroll (11%) and, during follow-up, exaggerating their enthusiasm for the study gel (13%), applicator (13%), and the effect of the gel on sexual pleasure (13%). In general, women who were untruthful had actually used the gel with condoms less and used the gel alone more than they had reported during the trial. Women overwhelmingly found the computer survey easy. Conclusion: Researchers cannot assume that participants always tell the truth about sensitive behaviors in face-to-face interviews. ACASI was efficient and acceptable in this population. © 2009 Elsevier Inc. All rights reserved.
Authors & Co-Authors
Turner, Abigail Norris
South Africa, Johannesburg
Population Council, Johannesburg
de Kock, Alana E.
South Africa, Cape Town
University of Cape Town
Meehan-Ritter, Amy
United States, Berkeley
University of California, Berkeley
Blanchard, Kelly
South Africa, Johannesburg
Population Council, Johannesburg
Sebola, Mohlatlego H.
South Africa, Pretoria
Sefako Makgatho Health Sciences University Smu
Hoosen, Anwar Ahmed
South Africa, Pretoria
Sefako Makgatho Health Sciences University Smu
Coetzee, Nicol
South Africa, Cape Town
University of Cape Town
Ellertson, Charlotte E.
South Africa, Johannesburg
Population Council, Johannesburg
Statistics
Citations: 68
Authors: 8
Affiliations: 4
Identifiers
Doi:
10.1016/j.jclinepi.2008.07.011
ISSN:
08954356
Research Areas
Sexual And Reproductive Health
Study Design
Randomised Control Trial
Cross Sectional Study
Cohort Study
Study Approach
Quantitative
Participants Gender
Female