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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Outcome of pregnancy in patients with structural or ischaemic heart disease: Results of a registry of the European Society of Cardiology
European Heart Journal, Volume 34, No. 9, Year 2013
Notification
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Description
AimsTo describe the outcome of pregnancy in patients with structural or ischaemic heart disease.Methods and resultsIn 2007, the European Registry on Pregnancy and Heart disease was initiated by the European Society of Cardiology. Consecutive patients with valvular heart disease, congenital heart disease, ischaemic heart disease (IHD), or cardiomyopathy (CMP) presenting with pregnancy were enrolled. Data for the normal population were derived from the literature. Sixty hospitals in 28 countries enrolled 1321 pregnant women between 2007 and 2011. Median maternal age was 30 years (range 16-53). Most patients were in NYHA class I (72%). Congenital heart disease (66%) was most prevalent, followed by valvular heart disease 25%, CMP 7%, and IHD in 2%. Maternal death occurred in 1%, compared with 0.007% in the normal population. Highest maternal mortality was found in patients with CMP. During pregnancy, 338 patients (26%) were hospitalized, 133 for heart failure. Caesarean section was performed in 41%. Foetal mortality occurred in 1.7% and neonatal mortality in 0.6%, both higher than in the normal population. Median duration of pregnancy was 38 weeks (range 24-42) and median birth weight 3010 g (range 300-4850). In centres of developing countries, maternal and foetal mortality was higher than in centres of developed countries (3.9 vs. 0.6%, P < 0.001 and 6.5 vs. 0.9% P < 0.001)ConclusionThe vast majority of patients can go safely through pregnancy and delivery as long as adequate pre-pregnancy evaluation and specialized high-quality care during pregnancy and delivery are available. Pregnancy outcomes were markedly worse in patients with CMP and in developing countries. © 2012 Published on behalf of the European Society of Cardiology. All rights reserved. © 2012 The Author.
Authors & Co-Authors
Roos-Hesselink, Jolien W.
Netherlands, Rotterdam
Erasmus Mc
Ruys, Titia P.E.
Netherlands, Rotterdam
Erasmus Mc
Stein, Joerg Ingolf
Austria, Innsbruck
Medizinische Universitat Innsbruck
Thilén, Ulf J.
Sweden, Lund
Skånes Universitetssjukhus
Webb, Gary
United States, Cincinnati
Cincinnati Children's Hospital Medical Center
Niwa, Kouichirou
Japan, Tokyo
St. Luke's International Hospital Tokyo
Kaemmerer, Harald
Unknown Affiliation
Baumgartner, Helmut R.
Germany, Munster
Adult Congenital and Valvular Heart Center
Budts, Werner I.H.L.
Belgium, Louvain
University Hospitals
Maggioni, Aldo Pietro
Italy, Florence
Associazione Nazionale Medici Cardiologi Ospedalieri
Tavazzi, Luigi T.
Italy, Cotignola
Maria Cecilia Hospital
Taha, Nasser Mohammad
Egypt, Minya
Al-minya University Hospital
Johnson, Mark Richard
United Kingdom, London
Imperial College London School of Medicine
Hall, Roger J.C.
United Kingdom, Norwich
University of East Anglia, Norwich Medical School
Statistics
Citations: 383
Authors: 14
Affiliations: 12
Identifiers
Doi:
10.1093/eurheartj/ehs270
ISSN:
0195668X
e-ISSN:
15229645
Research Areas
Maternal And Child Health
Noncommunicable Diseases
Sexual And Reproductive Health
Study Design
Cross Sectional Study
Participants Gender
Female