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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
HIV incidence among women of reproductive age in Malawi and Zimbabwe
Sexually Transmitted Diseases, Volume 33, No. 11, Year 2006
Notification
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Description
OBJECTIVE: The objective of this study was to determine the incidence of HIV-1. GOAL: The goal of this study was to inform HIV prevention and vaccine trials by conducting a multisite study in Malawi and Zimbabwe. STUDY DESIGN: Women of reproductive age were enrolled in a prospective study. They received 5 intensive HIV counseling and condom promotion sessions over 2 months. Subsequently, HIV-negative women completed quarterly follow-up visits. HIV incidence rates and predictors of HIV acquisition were assessed. RESULTS: A total of 2016 HIV-negative women were enrolled in the condom promotion and counseling phase of the study. Of these, 1679 were tested for HIV during follow up and 113 women seroconverted, resulting in an overall HIV incidence rate of 4.7 per 100 women-years (95% confidence interval = 3.8-5.6). Incidence rates were similar across sites. The major predictors of HIV acquisition were young age, presence of sexually transmitted infections, being unmarried, and higher educational level. CONCLUSION: The incidence of HIV continues to be high among women in both Malawi and Zimbabwe despite counseling and condom promotion. © Copyright 2006 American Sexually Transmitted Diseases Association.
Authors & Co-Authors
Kumwenda, Newton I.
United States, Baltimore
Johns Hopkins University
Hoffman, Irving F.
United States, Chapel Hill
The University of North Carolina at Chapel Hill
Chirenje, Mike Zvavahera
Zimbabwe, Harare
University of Zimbabwe
Kelly, Clifton W.
United States, Seattle
Fred Hutchinson Cancer Research Center
Coletti, Anne Schwartz
United States, Durham
Fhi 360
Ristow, A.
United States, Baltimore
Johns Hopkins University
Martinson, Francis E.A.
United States, Chapel Hill
The University of North Carolina at Chapel Hill
Brown, Joelle Morgan
United States, San Francisco
University of California, San Francisco
Chilongozi, David A.T.
Malawi, Lilongwe
Unc Project-malawi
Richardson, Barbra Ann
United States, Seattle
Fred Hutchinson Cancer Research Center
United States, Seattle
University of Washington
Rosenberg, Zeda F.
United States, Silver Spring
International Partnership for Microbicides
Padian, Nancy S.
United States, San Francisco
University of California, San Francisco
Taha, Taha E.
United States, Baltimore
Johns Hopkins University
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Statistics
Citations: 41
Authors: 13
Affiliations: 10
Identifiers
Doi:
10.1097/01.olq.0000223283.27142.9f
ISSN:
01485717
Research Areas
Infectious Diseases
Sexual And Reproductive Health
Study Design
Cohort Study
Study Locations
Malawi
Zimbabwe
Participants Gender
Female