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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
The cameroon mobile phone sms (CAMPS) trial: A protocol for a randomized controlled trial of mobile phone text messaging versus usual care for improving adherence to highly active anti-retroviral therapy
Trials, Volume 12, Article 5, Year 2011
Notification
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Description
Background: This trial aims at testing the efficacy of weekly reminder and motivational text messages, compared to usual care in improving adherence to Highly Active Antiretroviral Treatment in patients attending a clinic in Yaoundé, Cameroon.Methods and Design: This is a single-centered randomized controlled single-blinded trial. A central computer generated randomization list will be generated using random block sizes. Allocation will be determined by sequentially numbered sealed opaque envelopes. 198 participants will either receive the mobile phone text message or usual care. Our hypothesis is that weekly motivational text messages can improve adherence to Highly Active Antiretroviral Treatment and other clinical outcomes in the control group by acting as a reminder, a cue to action and opening communication channels. Data will be collected at baseline, three months and six months. A blinded program secretary will send out text messages and record delivery.Our primary outcomes are adherence measured by the visual analogue scale, self report, and pharmacy refill data. Our secondary outcomes are clinical: weight, body mass index, opportunistic infections, all cause mortality and retention; biological: Cluster Designation 4 count and viral load; and quality of life. Analysis will be by intention-to-treat. Covariates and subgroups will be taken into account.Discussion: This trial investigates the potential of SMS motivational reminders to improve adherence to Highly Active Antiretroviral Treatment in Cameroon. The intervention targets non-adherence due to forgetfulness and other forms of non-adherence.Trial Registration: Pan-African Clinical Trials Registry PACTR201011000261458. http://clinicaltrials.gov/NCT01247181. © 2011 Mbuagbaw et al; licensee BioMed Central Ltd.
Authors & Co-Authors
Mbuagbaw, Lawrence C.E.
Cameroon, Yaounde
Central Hospital of Yaounde Fmbs
Thabane, Lehana
Canada, Hamilton
Mcmaster University
Canada, Hamilton
St. Joseph's Healthcare Hamilton
Ongolo-Zogo, Pierre
Cameroon, Yaounde
Central Hospital of Yaounde Fmbs
Lester, Richard T.
Canada, Vancouver
The University of British Columbia
Canada, Vancouver
Bc Centre for Disease Control
Mills, Edward J.
Canada, Ottawa
University of Ottawa
Volmink, Jimmy A.
South Africa, Stellenbosch
Stellenbosch University
Yondo, David
Cameroon, Yaounde
Central Hospital of Yaounde Fmbs
Essi, Marie J.
Cameroon, Yaounde
Central Hospital of Yaounde Fmbs
Bonono-Momnougui, Renée Cécile
Cameroon, Yaounde
Central Hospital of Yaounde Fmbs
Mba, Robert
Cameroon, Yaounde
Central Hospital of Yaounde Fmbs
Ndongo, Jean S.
Cameroon, Yaounde
Central Hospital of Yaounde Fmbs
Nkoa, Francois C.
Cameroon, Yaounde
Central Hospital of Yaounde Fmbs
Ondoa, Henri Atangana
Cameroon, Yaounde
Central Hospital of Yaounde Fmbs
Statistics
Citations: 74
Authors: 13
Affiliations: 7
Identifiers
Doi:
10.1186/1745-6215-12-5
ISSN:
17456215
e-ISSN:
17456215
Research Areas
Disability
Health System And Policy
Study Design
Randomised Control Trial
Study Approach
Quantitative
Study Locations
Cameroon