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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Evaluation of the diethylcarbamazine patch to evaluate onchocerciasis endemicity in Central Africa
Tropical Medicine and International Health, Volume 12, No. 1, Year 2007
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Description
Objective: As part of a baseline data collection for assessing the impact of the African Programme for Onchocerciasis Control, to evaluate the diethylcarbamazine (DEC) patch test in determining the endemicity of onchocerciasis. Method: A total of 226 untreated children aged 3-5, living in four selected endemic foci, in Cameroon, Gabon and Central African Republic, were tested. Observed graded skin reactions to the patch were analysed and compared with the prevalence of onchocercal nodules and reactive skin disease in the corresponding community. Results: The proportion of children who tested positive ranged from 25.0% to 77.1%. The values were closely correlated with the prevalence of nodules, i.e. the level of endemicity for onchocerciasis. Conclusion: The DEC patch test, which has been so far used only in West African foci of onchocerciasis, can also constitute a valuable tool to evaluate the levels of endemicity of onchocerciasis in Central Africa, and to follow-up the intensity of transmission of Onchocerca volvulus. © 2007 Blackwell Publishing Ltd.
Authors & Co-Authors
Ozoh, Gladys Angela O.
Nigeria, Naukka
University of Nigeria
Boussinesq, Michel
France, Marseille
Ird Institut de Recherche Pour le Developpement
Bissek, Anne Cécile Zoung Kanyi
Cameroon, Yaounde
Université de Yaoundé I Faculté de Médecine
Kobangué, Léon
Central African Republic
Centre National Hospitalier Universitaire
Kombila, Maryvonne Y.
Gabon, Libreville
Faculte de Medecine et Des Sciences de la Sante
Mbina, Jean Romain Mourou
Gabon, Libreville
Faculte de Medecine et Des Sciences de la Sante
Enyong, Peter Ayuk I.
Cameroon
Tropical Medicine Research Station
Noma, Mounkaïla M.
Switzerland, Geneva
Organisation Mondiale de la Santé
Sékétéli, Azodoga V.
Switzerland, Geneva
Organisation Mondiale de la Santé
Burkina Faso, Ouagadougou
African Programme for Onchocerciasis Control
Fobi, Grace
Switzerland, Geneva
Organisation Mondiale de la Santé
Statistics
Citations: 31
Authors: 10
Affiliations: 8
Identifiers
Doi:
10.1111/j.1365-3156.2006.01750.x
ISSN:
13602276
e-ISSN:
13653156
Research Areas
Infectious Diseases
Maternal And Child Health
Study Design
Cross Sectional Study
Cohort Study
Grounded Theory
Study Locations
Cameroon
Central African Republic
Gabon