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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Abnormalities of auditory event-related potentials in students with high scores on the Schizotypal Personality Questionnaire
Psychiatry Research, Volume 144, No. 2-3, Year 2006
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Description
Some auditory event-related potential (ERP) abnormalities characterize both patients with schizophrenia and subjects with schizotypal personality disorder. It was therefore hypothesized that subjects from the community with schizotypal traits might also present ERP abnormalities. In this study, we compared auditory ERP latencies and amplitudes in 13 subjects with high (H-SPQ) and 12 subjects with low (L-SPQ) scores on the Schizotypal Personality Questionnaire (SPQ), selected from 198 Tunisian students. Auditory ERPs were recorded at Fz, Cz, and Pz, with a standard oddball paradigm. Smaller P300 amplitudes and delayed P300 latencies were found in H-SPQ compared with L-SPQ participants. Confirming previous reports, our results suggest that reduced P300 amplitudes and delayed P300 latencies may be considered as vulnerability markers of the schizophrenia spectrum in nonclinical subjects from the community. © 2005 Elsevier Ireland Ltd. All rights reserved.
Authors & Co-Authors
Gassab, Leila
Tunisia, Monastir
Faculté de Médecine de Monastir
Mechri, A.
Tunisia, Monastir
Faculté de Médecine de Monastir
Dogui, Mohamed H.
Tunisia, Sousse
Chu Sahloul
Gaha, Lotfi
Tunisia, Monastir
Faculté de Médecine de Monastir
D'Amato, Thierry A.
France, Villeurbanne
Université Claude Bernard Lyon 1
Daléry, Jean
France, Villeurbanne
Université Claude Bernard Lyon 1
Saoud, Mohamed
France, Villeurbanne
Université Claude Bernard Lyon 1
Statistics
Citations: 15
Authors: 7
Affiliations: 3
Identifiers
Doi:
10.1016/j.psychres.2004.09.010
ISSN:
01651781
Research Areas
Mental Health