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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Prevalence of type 2 diabetes in algerian patients with hepatitis C virus infection
World Journal of Gastroenterology, Volume 16, No. 27, Year 2010
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Description
AIM: To investigate the prevalence of, and risk factors for, diabetes mellitus (DM) in Algerian patients with chronic hepatitis C virus (HCV) infection and in a control group. METHODS: A cross-sectional study was undertaken. A total of 416 consecutive patients with viral chronic hepatitis attending the Internal Medicine Department of the University Hospital Center Touhami Benflis in Batna [290 HCV-infected and 126 hepatitis B virus (HBV)-infected patients] were prospectively recruited. RESULTS: The prevalence of DM was higher in HCV-infected patients in comparison with HBV-infected patients (39.1% vs 5%, P < 0.0001). Among patients without cirrhosis, diabetes was more prevalent in HCV-infected patients than in HBV-infected patients (33.5% vs 4.3%, P < 0.0001). Among patients with cirrhosis, diabetes was more prevalent in HCV-infected patients, but the difference was not significant (67.4% vs 20%, P = 0.058). The logistic regression analysis showed that HCV infection [odds ratio (OR) 4.73, 95% CI: 1.7-13.2], metabolic syndrome (OR 12.35, 95% CI: 6.18-24.67), family history of diabetes (OR 3.2, 95% CI: 1.67-6.13) and increased hepatic enzymes (OR 2.22, 95% CI: 1.1-4.5) were independently related to DM in these patients. CONCLUSION: The high prevalence of diabetes in HCV-infected patients, and its occurrence at early stages of hepatic disease, suggest that screening for glucose abnormalities should be indicated in these patients. © 2010 Baishideng.
Authors & Co-Authors
Rouabhia, Samir
Algeria, Batna
Centre Hospitalo-universitaire Touhami Benflis - Batna
Malek, Rachid
Algeria, Setif
Centre Hospitalo-universitaire Saadna Mohamed Abdenour - Sétif
Bounecer, Hocine
Algeria, Batna
Centre Hospitalo-universitaire Touhami Benflis - Batna
Dekaken, Aoulia
Algeria, Batna
Centre Hospitalo-universitaire Touhami Benflis - Batna
Amor, Fouzia Bendali
Algeria, Batna
Centre Hospitalo-universitaire Touhami Benflis - Batna
Sadelaoud, Mourad
Algeria, Batna
Sadelaoud Laboratory of Medical Biology
Benouar, Abderrahmene
Algeria, Batna
Centre Hospitalo-universitaire Touhami Benflis - Batna
Statistics
Citations: 53
Authors: 7
Affiliations: 3
Identifiers
Doi:
10.3748/wjg.v16.i27.3427
ISSN:
10079327
Research Areas
Health System And Policy
Infectious Diseases
Noncommunicable Diseases
Study Design
Randomised Control Trial
Cross Sectional Study
Case-Control Study
Study Approach
Quantitative