Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
The international HIV dementia scale is a useful screening tool for HIV-associated dementia/cognitive impairment in HIV-infected adults in Yaoundé - Cameroon
Journal of Acquired Immune Deficiency Syndromes, Volume 49, No. 4, Year 2008
Notification
URL copied to clipboard!
Description
Objective: As a baseline for a series of studies on HIV-associated dementia (HAD), we sought to assess the usefulness of the recently developed International HIV Dementia Scale (IHDS) as a screening tool for HAD or HIV-associated cognitive impairment (HACI) in HIV-positive adults in Yaoundé - Cameroon. Design: The frequency of HAD/HACI is largely unknown in resource-limited countries. In Cameroon, few studies suggest that HAD may be frequent but no specific study had so far investigated the problem. We therefore used a case-control study design involving HIV-positive adults as cases and HIV-negative individuals as controls to determine the usefulness of the IHDS as a screening instrument. Methods: HIV-positive adults followed up in an HIV outpatient clinic were matched to HIV-negative subjects for age and sex and screened using IHDS. Results: Overall, 204 HIV-positive individuals and 204 HIV-negative subjects were screened. The HIV-positive subjects had a significantly lower IHDS mean total score of 10.87 compared with the HIV-negative subjects with a score of 11.28 (P = 0.00). Abnormal scores (≤10) on the IHDS were found in 21.1% of the HIV-positive subjects and in 2.5% of the HIV-negative subjects (P = 5.0 × 10-10). Conclusions: These results suggest that the prevalence of possible HAD/HACI may be higher in Cameroon than the previous estimates and demonstrate that the IHDS can be used as a screening tool for HAD in Cameroon. We therefore suggest that all studies on HAD in Cameroon should strategically start with the IHDS as a screening tool. Copyright © 2008 by Lippincott Williams & Wilkins.
Authors & Co-Authors
Njamnshi, Alfred Kongnyu
Cameroon, Yaounde
Université de Yaoundé I
Cameroon, Yaounde
Central Hospital of Yaounde Fmbs
Djientcheu, Vincent De Paul
Unknown Affiliation
Fonsah, Julius Yundze
Cameroon, Yaounde
Central Hospital of Yaounde Fmbs
Cameroon, Yaounde
Université de Yaoundé I
Yepnjio, Faustin Njionda
Cameroon, Yaounde
Central Hospital of Yaounde Fmbs
Njamnshi, Dora Mugha
Cameroon, Yaounde
Central Hospital of Yaounde Fmbs
Muna, Walinjom Fombad T.
Cameroon, Yaounde
Université de Yaoundé I
Statistics
Citations: 50
Authors: 6
Affiliations: 2
Identifiers
Doi:
10.1097/QAI.0b013e318183a9df
ISSN:
15254135
Research Areas
Health System And Policy
Infectious Diseases
Mental Health
Study Design
Cross Sectional Study
Case-Control Study
Study Locations
Cameroon