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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Ascertainment of childhood vaccination histories in northern Malawi
Tropical Medicine and International Health, Volume 13, No. 1, Year 2008
Notification
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Description
Objective: To assess factors related to recorded vaccine uptake, which may confound the evaluation of vaccine impact. Methods: Analysis of documented vaccination histories of children under 5 years and demographic and socio-economic characteristics collected by a demographic surveillance system in Karonga District, Malawi. Associations between deviations from the standard vaccination schedule and characteristics that are likely to be associated with increased mortality were determined by multivariate logistic regression. Results: Approximately 78% of children aged 6-23 months had a vaccination document, declining to <50% by 5 years of age. Living closer to an under-5 clinic, having a better educated father, and both parents being alive were associated with having a vaccination document. For a small percentage of children, vaccination records were incomplete and/or faulty. Vaccination uptake was high overall, but delayed among children living further from the nearest under-5 clinic or from poorer socio-economic backgrounds. Approximately 9% of children had received their last dose of DPT with or after measles vaccine. These children were from relatively less educated parents, and were more likely to have been born outside the health services. Conclusions: Though overall coverage in this community was high and variation in coverage according to child or parental characteristics small, there was strong evidence of more timely coverage among children from better socio-economic conditions and among those who lived closer to health facilities. These factors are likely to be strong confounders in the association of vaccinations with mortality, and may offer an alternative explanation for the non-specific mortality impact of vaccines described by other studies. © 2008 Blackwell Publishing Ltd.
Authors & Co-Authors
Jahn, Andreas
Unknown Affiliation
Floyd, Sian
Unknown Affiliation
Mwinuka, V.
Unknown Affiliation
Mwafilaso, J. B.
Unknown Affiliation
Mwagomba, Dennis
Unknown Affiliation
Mkisi, Rouden Esau
Unknown Affiliation
Katsulukuta, Agnes
Unknown Affiliation
Khunga, A.
Unknown Affiliation
Crampin, Amelia Catharine
Unknown Affiliation
Branson, Keith
Unknown Affiliation
McGrath, Nuala M.
Unknown Affiliation
Fine, Paul E.M.
Unknown Affiliation
Statistics
Citations: 39
Authors: 12
Affiliations: 6
Identifiers
Doi:
10.1111/j.1365-3156.2007.01982.x
ISSN:
13602276
e-ISSN:
13653156
Research Areas
Health System And Policy
Infectious Diseases
Maternal And Child Health
Study Locations
Malawi