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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Recurrent deep vein thrombosis, ovarian carcinoma and antibodies to mitochondria M5 in a patient with asymptomatic primary "plus" antiphospholipid syndrome: An unusual combination
Clinical and Experimental Rheumatology, Volume 25, No. 6, Year 2007
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Description
An symptomatic thirty-eight-year-old female developed recurrent DVT at the latter end of her first pregnancy and in the puerperium. Blood tests revealed a moderately elevated ANF (1:640) with a speckled pattern, hyperglobulinemia, and antibodies to thyroid tissues. Two months postpartum, following neurological disturbances she was found to have a patent foramen ovale and had developed paradoxical emboli to the brain causing multiple arterial occlusions. However, she also had cerebral venous occlusions as well as deep venous thromboses and pulmonary emboli, indicating a generalised prothrombotic state. Abdominal ultrasound examination revealed the presence of tumour which, on surgical removal, proved to be an ovarian carcinoma. The only antiphosholipid antibodies detectable were antibodies to mitochondria Type M5 in moderately elevated titres. © Copyright Clinical Experimental Rheumatology 2007.
Authors & Co-Authors
Asherson, Ronald A.
South Africa, Johannesburg
School of Pathology
Schamroth-Rapaport, Naomi
South Africa, Johannesburg
Millpark Hospital
Skudowitz, Ben
South Africa, Johannesburg
Lancet Laboratories
Singh, Sham
South Africa, Johannesburg
Lancet Laboratories
Marx, David
South Africa, Johannesburg
Rosebank Clinic
Germany, Frankfurt am Main
Goethe-universität Frankfurt am Main
Miesbach, W. A.
South Africa, Johannesburg
Rosebank Clinic
Germany, Frankfurt am Main
Goethe-universität Frankfurt am Main
Statistics
Citations: 6
Authors: 6
Affiliations: 5
Identifiers
ISSN:
0392856X
Research Areas
Cancer
Health System And Policy
Maternal And Child Health
Sexual And Reproductive Health
Participants Gender
Female