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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Can Plasma Fructosamine Substitute for Glycated Haemoglobin (HbA
1c
) Estimation in the Assessment of Diabetic Control?
Tropical Doctor, Volume 30, No. 2, Year 2000
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Description
The ‘gold standard’ marker of overall glycaemic control in diabetes mellitus is the level of glycated haemoglobin (HbA1c). It is, however, an expensive and technically difficult assay and is rarely appropriate to tropical laboratories. Plasma fructosamine measurement is cheaper and easier, though it reflects shorter-term glycaemia. We have measured both indices of control in a group of 154 diabetic patients. There was close correlation between the two measurements (=0.6506, P < 0.001), but many patients with abnormal HbA1c levels had normal fructosamine levels. This resulted in an assay sensitivity (compared with HbA1c as gold standard) of only 30%, though specificity was 98%. We conclude that fructosamine measurement cannot be regarded as a substitute for HbA1c determination. © 2000, SAGE Publications. All rights reserved.
Authors & Co-Authors
Malik, M.
United Arab Emirates, Abu Dhabi
Al Mafraq Hospital
Gill, Geoffrey V.
United Kingdom, Liverpool
Liverpool School of Tropical Medicine
Pugh, R. N.H.
United Arab Emirates, Al Ain
United Arab Emirates University
Bakir, Ali
United Arab Emirates, Abu Dhabi
Al Mafraq Hospital
Hossain, Munir Moshaddeque
United Arab Emirates, Al Ain
United Arab Emirates University
Statistics
Citations: 5
Authors: 5
Affiliations: 3
Identifiers
Doi:
10.1177/004947550003000206
ISSN:
00494755
e-ISSN:
17581133
Research Areas
Noncommunicable Diseases